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Urea, 1 - allyl - 2 - thio -

RTECS #: YR8050000

CAS #: 109-57-9

UPDATE: January 1997 MW: 116.20 MF: C4H8N2S


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. (2 - Propenyl) thiourea
  2. 1 - Allylthiourea
  3. 1 - Allyl - 2 - thiourea
  4. Allylthiocarbamide
  5. Allylthiomocovina (Czech)
  6. Allylthiourea
  7. Aminosin
  1. N - Allylthiourea
  2. Rhodallin
  3. Rhodalline
  4. Thiocynamine
  5. Thiosinamin
  6. Thiosinamine
  7. U 19571


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
mutation in microorganisms Salmonella typhimurium 150 µg/plate (+enzymatic activation step) ABCHA6 44,3017,1980


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 1,858 mg/kg N/R YKKZAJ 94,1419,1974
intraperitoneal
rat 		lethal dose (50 percent kill): 500 mg/kg Endocrine: Hyperglycemia JPETAB 89,186,1947
intravenous
dog 		lowest published lethal dose: 110 mg/kg N/R HBAMAK 4,1289,1935
oral
rat 		lethal dose (50 percent kill): 200 mg/kg N/R JPETAB 90,260,1947
subcutaneous
mouse 		lowest published lethal dose: 700 mg/kg N/R HBAMAK 4,1289,1935
subcutaneous
rat 		lowest published lethal dose: 50 mg/kg N/R HBAMAK 4,1289,1935


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83304;
Number of Industries 1;
Total Number of Facilities 10;
Number of Occupations 1;
Total Number of Employees Exposed 30
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83304;
Number of Industries 1;
Total Number of Facilities 15;
Number of Occupations 2;
Total Number of Employees Exposed 5,526;
Total Number of Female Employees Exposed 5,182


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961-
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.)
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881-

Used in photography and medicine, also used as corrosion inhibitor and in organic synthesis

NIOSH PROFILE (THIOUREA AND COMPOUNDS), SRC, 1/82

RTECS Compound Description:
   Drug
   Mutagen

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