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Tragacanth gum

RTECS #: XW7750000

CAS #: 9000-65-1

UPDATE: May 2009 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Gum tragacanth


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		610 µg mild JACTDZ 6(1),1,1987
skin
rabbit 		3,050 µg/24 hour mild JACTDZ 6(1),1,1987


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
hamster 		lethal dose (50 percent kill): 8,800 mg/kg N/R FDRLI* 124,-,1976
oral
mouse 		lethal dose (50 percent kill): 10 gm/kg N/R FDRLI* 124,-,1976
oral
rat 		lethal dose (50 percent kill): 10,200 mg/kg Behavioral: Ataxia

Kidney, Ureter, and Bladder: Urine volume increased

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		JACTDZ 6(1),1,1987
oral
rabbit 		lethal dose (50 percent kill): 7,200 mg/kg N/R FDRLI* 124,-,1976


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
HUTOX* -,259,1996


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
FDRLI* Food & Drug Research Laboratories, Inc., Papers. (P.O. Box 107, Rt. 17C, Waverly, NY 14892-0107)
HUTOX*
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.

Used as a cosmetic ingredient, food stabilizer and thickener

RTECS Compound Description:
   Natural Product
   Primary Irritant

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