RTECS:XI0337500 The Registry of Toxic Effects of Chemical Substances

5 - Thia - 1 - azabicyclo (4.2.0) oct - 2 - ene - 2 - carboxylic acid, 7 - ( (amino (4 - hydroxyphenyl) acetyl) amino) - 3 - methyl - 8 - oxo - , monohydrate, (6R - (6 - alpha,7 - beta (R*) ) ) -

RTECS #: XI0337500

CAS #: 66592-87-8

UPDATE: April 1995 MW: 381.44 MF: C₁₆H₁₇N₃O₅S•H₂O

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

ACUTE TOXICITY DATA:

NIOSH DOCUMENTATION AND SURVEILLANCE:

REFERENCES:

SYNONYMS:

Cefadroxil monohydrate

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
intraperitoneal
mouse lethal dose (50 percent kill): >6 gm/kg N/R IYKEDH 13,1128,1982
intraperitoneal
rat lethal dose (50 percent kill): >6 gm/kg N/R IYKEDH 13,1128,1982
oral
mouse lethal dose (50 percent kill): >10 gm/kg N/R IYKEDH 13,1128,1982
oral
rat lethal dose (50 percent kill): >10 gm/kg N/R IYKEDH 13,1128,1982
subcutaneous
mouse lethal dose (50 percent kill): >8 gm/kg N/R IYKEDH 13,1128,1982
subcutaneous
rat lethal dose (50 percent kill): >8 gm/kg N/R IYKEDH 13,1128,1982

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X5428;
Number of Industries 1;
Total Number of Facilities 16;
Number of Occupations 1;
Total Number of Employees Exposed 94;
Total Number of Female Employees Exposed 62

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

N/R

REFERENCES:
CODEN
REFERENCE

IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-

RTECS Compound Description:
Drug

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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST	ROUTE/ ORGANISM/ TISSUE	DOSE	REFERENCE
N/R	N/R	N/R	N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
intraperitoneal mouse	lethal dose (50 percent kill): >6 gm/kg	N/R	IYKEDH 13,1128,1982
intraperitoneal rat	lethal dose (50 percent kill): >6 gm/kg	N/R	IYKEDH 13,1128,1982
oral mouse	lethal dose (50 percent kill): >10 gm/kg	N/R	IYKEDH 13,1128,1982
oral rat	lethal dose (50 percent kill): >10 gm/kg	N/R	IYKEDH 13,1128,1982
subcutaneous mouse	lethal dose (50 percent kill): >8 gm/kg	N/R	IYKEDH 13,1128,1982
subcutaneous rat	lethal dose (50 percent kill): >8 gm/kg	N/R	IYKEDH 13,1128,1982

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

STANDARDS AND REGULATIONS:
ORGANIZATION	STANDARD	REFERENCE
N/R	N/R	N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION	STANDARD or SURVEY	REFERENCE
National Occupational Exposure Survey 1983	National Occupational Exposure Survey 1983: Hazard Code: X5428; Number of Industries 1; Total Number of Facilities 16; Number of Occupations 1; Total Number of Employees Exposed 94; Total Number of Female Employees Exposed 62

REFERENCES:
CODEN	REFERENCE
IYKEDH	Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970-