CDC logo, Safer Healthier People CDC HomeCDC SearchCDC Health Topics A-Z
NIOSH - National Institute for Occupational Safety and Health

Search NIOSH  |  NIOSH Home  |  NIOSH Topics  |  Site Index  |  Databases and Information Resources  |  NIOSH Products  |  Contact Us




Tellurium dioxide

RTECS #: WY2675000

CAS #: 7446-07-3

UPDATE: May 2009 MW: 159.60 MF: O2Te


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. REPRODUCTIVE EFFECTS DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. REVIEWS:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. Tellurium oxide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 1 µg/m3 (1-20 day pregnant) Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Effects on embryo or fetus: Fetal death 		VCVN5* -,288,1989
subcutaneous
rat 		lowest published toxic dose: 798 mg/kg (15-19 day pregnant) Reproductive: Effects on embryo or fetus: Fetal death

Reproductive: Specific developmental abnormalities: Central nervous system

Reproductive: Specific developmental abnormalities: Eye, ear 		TJADAB 29(2),50A,1984
subcutaneous
rat 		lowest published toxic dose: 798 mg/kg (15-19 day pregnant) Reproductive: Specific developmental abnormalities: Body wall

Reproductive: Specific developmental abnormalities: Urogenital system

Reproductive: Specific developmental abnormalities: Homeostasis 		TJADAB 29(2),50A,1984
subcutaneous
rat 		lowest published toxic dose: 399 mg/kg (15-19 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) TJADAB 29(2),50A,1984
subcutaneous
rat 		lowest published toxic dose: 27,930 µg/kg (15-19 day pregnant) Reproductive: Specific developmental abnormalities: Central nervous system

Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive) 		TJADAB 31,66A,1985
subcutaneous
rat 		lowest published toxic dose: 79,800 µg/kg (15-19 day pregnant) Reproductive: Effects on newborn: Stillbirth TJADAB 31,66A,1985


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intratracheal
rat 		lowest published lethal dose: 80 mg/kg Lung, Thorax, or Respiration: Dyspnea

Kidney, Ureter, and Bladder: Other changes

Gastrointestinal: Other changes 		AIHAAP 39,100,1978
oral
mammal (species unspecified) 		lowest published lethal dose: 2.5 mg/kg N/R VCVN5* -,288,1993
oral
rat 		lethal dose (50 percent kill): >5 gm/kg Gastrointestinal: Hypermotility, diarrhea TNONF* TNO-96-514
unreported route
rabbit 		lowest published lethal dose: 324 mg/kg N/R SMSJAR 26,131,1826


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 50 mg/m3/2 hour/15 week- intermittent Autonomic Nervous System: Other (direct) parasympathomimetic

Behavioral: Muscle contraction or spasticity

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		GTPZAB 6(2),44,1962
inhalation
rat 		lowest published toxic concentration: 3,500 ng/kg/13 week- continuous Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases 		GISAAA 40(10),14,1975
inhalation
rat 		lowest published toxic concentration: 10 mg/m3/13 week- intermittent Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Kidney, Ureter, and Bladder: Changes primarily in glomeruli

Blood: Hemorrhage 		HBTME* -,815,2007
inhalation
rat 		lowest published toxic concentration: 50 mg/m3/13 week- intermittent Kidney, Ureter, and Bladder: Hematuria

Blood: Other hemolysis with or without anemia

Blood: Changes in erythrocyte (RBC) count 		HBTME* -,815,2007


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.1 mg(Te)/m3 DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
HBTME* ,815,2007


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.1 mg(Te)/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.1 mg(Te)/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.1 mg(Te)/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.1 mg(Te)/m3 CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.1 mg(Te)/m3, JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 0.1 mg(Te)/m3, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 0.1 mg(Te)/m3, OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 0.1 mg(Te)/m3, short term exposure limit 0.3 mg(Te)/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 0.1 mg(Te)/m3, FEB2006
Occupational Exposure Limit - MEXICO time-weighted average 0.1 mg(Te)/m3, 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.1 mg(Te)/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 0.1 mg(Te)/m3, JAN2002
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.1 mg(Te)/m3, JAN1993
Occupational Exposure Limit - SWEDEN time-weighted average 0.1 mg(Te)/m3, JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 0.1 mg(Te)/m3,KZG- week 0.2 mg(Te)/m3, DEC2006
Occupational Exposure Limit - TURKEY time-weighted average 0.1 mg(Te)/m3, JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.1 mg(Te)/m3, 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 0.1 mg(Te)/m3
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 0.1 mg(Te)/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83727;
Number of Industries 1;
Total Number of Facilities 125;
Number of Occupations 2;
Total Number of Employees Exposed 502
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83727;
Number of Industries 1;
Total Number of Facilities 6;
Number of Occupations 1;
Total Number of Employees Exposed 51


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
HBTME*
SMSJAR Scottish Medical and Surgical Journal. (Edinburgh, Scotland) For publisher information, see SMDJAK.
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
TNONF* TNO-report. (TNO Nutrition and Food Research, P.O. Box 360, 3700 AJ Zeist, Utrechtseweg 48, 3704 HE Zeist, Netherlands)
VCVN5* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.

NIOSH PROFILE (HAIRDRESSING and BARBERS), SRC, 6/80

RTECS Compound Description:
   Reproductive Effector

 Click Here for Additional Information about RTECS

NIOSH Home |  NIOSH Search  |  Site Index  |  Topic List |  Contact Us