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Sulfuric acid, aluminum potassium salt (2:1:1)

RTECS #: WS5650000

CAS #: 10043-67-1

UPDATE: May 2008 MW: 258.20 MF: O8S2•Al•K


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Alum potassium
  2. Aluminum potassium alum
  3. Aluminum potassium disulfate
  4. Aluminum potassium sulfate
  5. Aluminum potassium sulfate, alum
  6. Aluminum potassium sulfate, anhydrous
  1. Burnt alum
  2. Burnt potassium alum
  3. Dialuminum dipotassium sulfate
  4. Exsiccated alum
  5. Potash alum
  6. Potassium aluminum sulfate (1:1:2)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
mutation in microorganisms other microorganisms 50 µmol/L (-enzymatic activation step) MUREAV 264,135,1991
other mutation test systems oral
rat 		824 mg/kg/7 day- continuous CYTBAI 66,105,1991


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 4,355 mg/kg/26 week- intermittent Behavioral: Alteration of classical conditioning

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases 		GISAAA 43(5),101,1978
oral
rat 		lowest published toxic dose: 8,040 mg/kg/67 day- continuous Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Nutritional and Gross Metabolic: Changes in: P 		FAATDF 10,616,1988
oral
rat 		lowest published toxic dose: 456.2 mg/kg/26 week- intermittent Reproductive: Paternal effects: Testes, epididymis, sperm duct

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases 		VCVN1* -,215,1988


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - FRANCE VME 2 mg(Al)/m3, FEB2006
Occupational Exposure Limit - KOREA time-weighted average 2 mg(Al)/m3, 2006
Occupational Exposure Limit - NEW ZEALAND time-weighted average 2 mg(Al)/m3, JAN2002
Occupational Exposure Limit - SWEDEN time-weighted average 1 mg(Al)/m3, JUN2005


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X4506;
Number of Industries 7;
Total Number of Facilities 744;
Number of Occupations 12;
Total Number of Employees Exposed 8,512;
Total Number of Female Employees Exposed 1,433


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as a food additive
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
CYTBAI Cytobios. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 1969-
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
VCVN1* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.

Used as a food additive

NIOSH PROFILE (PHOTOGRAPHIC PROCESSING), FIRL, 4/78

NIOSH PROFILE (ALUMINUM and ITS COMPOUNDS), SRC, 1/81

FDA-over the counter drug

RTECS Compound Description:
   Mutagen

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