07-08-2009 FILE: RTECSWEB.TXT 389,119 Total Lines 9,813 Chemical Prime Names (A010) 9,813 RTECS Numbers (G010) 9,813 Updates (E010) 89,352 Chemical Synonyms (L) 0 Cross References (B001) 9,415 Primary CAS Numbers (D010) 1,842 Alternate CAS Numbers (D5) 2,700 Beilstein Handbook References (D600) 3,465 Beilstein Registry Numbers (D610) 8,838 Molecular Formulas (F010) 8,607 Molecular Weights (H010) 6,143 Wiswesser Line Notations (J010) Compound Descriptor Codes (N): 1,736 CDC:A Agricultural Chemical (Cited in 1,736 chemicals.) 1,763 CDC:C Tumorigen (Cited in 1,763 chemicals.) 1,971 CDC:D Drug (Cited in 1,971 chemicals.) 141 CDC:H Hormone (Cited in 141 chemicals.) 2,820 CDC:M Mutagen (Cited in 2,820 chemicals.) 537 CDC:N Natural Product (Cited in 537 chemicals.) 566 CDC:O Organometallic (Cited in 566 chemicals.) 2,069 CDC:P Human Data (Cited in 2,069 chemicals.) 1,798 CDC:S Primary Irritant (Cited in 1,798 chemicals.) 1,864 CDC:T Reproductive Effector (Cited in 1,864 chemicals.) Species Codes (P, Q, R, S, T, U): 164 SPC:asn Aspergillus nidulans (Cited in 119 chemicals.) 383 SPC:bcs Bacillus subtilis (Cited in 311 chemicals.) 108 SPC:brd Domestic Bird (Cited in 73 chemicals.) 251 SPC:bwd Wild Bird (Cited in 233 chemicals.) 1,028 SPC:cat Cat (Cited in 667 chemicals.) 371 SPC:chd Child (Cited in 231 chemicals.) 697 SPC:ckn Chicken (Cited in 423 chemicals.) 11 SPC:clr Chlamydomonas reinhardi (Cited in 11 chemicals.) 180 SPC:ctl Cattle (Cited in 106 chemicals.) 215 SPC:dck Duck (Cited in 175 chemicals.) 768 SPC:dmg Drosophila melanogaster (Cited in 366 chemicals.) 2,590 SPC:dog Dog (Cited in 1,333 chemicals.) 344 SPC:dom Domestic Animal (Cited in 209 chemicals.) 1,276 SPC:esc Escherichia coli (Cited in 662 chemicals.) 17 SPC:eug Euglena gracilis (Cited in 14 chemicals.) 318 SPC:frg Frog (Cited in 251 chemicals.) 3,145 SPC:gpg Guinea Pig (Cited in 1,722 chemicals.) 57 SPC:grb Gerbil (Cited in 37 chemicals.) 42 SPC:grh Grasshopper (Cited in 31 chemicals.) 4,646 SPC:ham Hamster (Cited in 1,274 chemicals.) 20 SPC:hmi Haemophilus influenzae (Cited in 13 chemicals.) 5,960 SPC:hmn Human (Cited in 1,685 chemicals.) 48 SPC:hor Horse, Donkey (Cited in 24 chemicals.) 125 SPC:inf Infant (Cited in 88 chemicals.) 33 SPC:klp Klebsiella pneumoniae (Cited in 33 chemicals.) 1,580 SPC:mam Mammal (species unspecified) (Cited in 956 chemicals.) 1,566 SPC:man Man (Cited in 699 chemicals.) 1,026 SPC:mky Monkey (Cited in 453 chemicals.) 30,575 SPC:mus Mouse (Cited in 6,126 chemicals.) 291 SPC:nml Non-Mammalian Species (Cited in 148 chemicals.) 77 SPC:nsc Neurospora crassa (Cited in 72 chemicals.) 169 SPC:ofs Other fish (Cited in 75 chemicals.) 97 SPC:oin Other insects (Cited in 48 chemicals.) 673 SPC:omi Other microorganisms (Cited in 231 chemicals.) 169 SPC:pgn Pigeon (Cited in 139 chemicals.) 339 SPC:pig Pig (Cited in 193 chemicals.) 296 SPC:qal Quail (Cited in 251 chemicals.) 45,259 SPC:rat Rat (Cited in 7,465 chemicals.) 9,552 SPC:rbt Rabbit (Cited in 3,835 chemicals.) 39 SPC:sal Salmon (Cited in 35 chemicals.) 2,151 SPC:sat Salmonella typhimurium (Cited in 1,170 chemicals.) 21 SPC:slw Silkworm (Cited in 15 chemicals.) 674 SPC:smc Saccharomyes cerevisiae (Cited in 384 chemicals.) 6 SPC:sql Squirrel (Cited in 4 chemicals.) 8 SPC:srm Serratia marcescens (Cited in 8 chemicals.) 64 SPC:ssp Schizosaccharomyces pombe (Cited in 48 chemicals.) 2 SPC:tod Toad (Cited in 2 chemicals.) 20 SPC:trk Turkey (Cited in 14 chemicals.) 1,608 SPC:wmn Woman (Cited in 566 chemicals.) Toxic Effects Codes (R, S, T, U): 10 TEC:A01 Brain and Coverings: Meningeal changes (Cited in 8 chemicals.) 11 TEC:A02 Brain and Coverings: Changes in cerebral spinal fluid (Cited in 11 chemicals.) 58 TEC:A03 Brain and Coverings: Increased intracranial pressure (Cited in 30 chemicals.) 160 TEC:A04 Brain and Coverings: Changes in circulation (Cited in 104 chemicals.) 15 TEC:A05 Brain and Coverings: Encephalitis (Cited in 11 chemicals.) 22 TEC:A06 Brain and Coverings: Demyelination (Cited in 17 chemicals.) 150 TEC:A10 Brain and Coverings: Changes in surface EEG (Cited in 102 chemicals.) 401 TEC:A11 Brain and Coverings: Recordings from specific areas of CNS (Cited in 283 chemicals.) 1,656 TEC:A30 Brain and Coverings: Other degenerative changes (Cited in 597 chemicals.) 111 TEC:A60 Brain and Coverings: Tumors (Cited in 52 chemicals.) 123 TEC:A70 Brain and Coverings: Changes in brain weight (Cited in 103 chemicals.) 4 TEC:B01 Spinal Cord: Meningeal changes (Cited in 4 chemicals.) 3 TEC:B02 Spinal Cord: Changes in circulation (Cited in 3 chemicals.) 8 TEC:B03 Spinal Cord: Inflammatory changes (Cited in 7 chemicals.) 22 TEC:B04 Spinal Cord: Demyelination (Cited in 19 chemicals.) 168 TEC:B30 Spinal Cord: Other degenerative changes (Cited in 81 chemicals.) 4 TEC:B60 Spinal Cord: Tumors (Cited in 4 chemicals.) 1 TEC:C01 Peripheral Nerve and Sensation: Associated connective tissue (Cited in 1 chemicals.) 18 TEC:C02 Peripheral Nerve and Sensation: Sensory syndrome diagnostic of central lesion (Cited in 15 chemicals.) 9 TEC:C03 Peripheral Nerve and Sensation: Sensory change involving trigeminal nerve (Cited in 7 chemicals.) 88 TEC:C04 Peripheral Nerve and Sensation: Sensory change involving peripheral nerve (Cited in 69 chemicals.) 29 TEC:C05 Peripheral Nerve and Sensation: Sensory change involving segmental distribution (Cited in 20 chemicals.) 276 TEC:C06 Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change (Cited in 202 chemicals.) 52 TEC:C07 Peripheral Nerve and Sensation: Flaccid paralysis with appropriate anesthesia (Cited in 29 chemicals.) 355 TEC:C08 Peripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage) (Cited in 224 chemicals.) 68 TEC:C09 Peripheral Nerve and Sensation: Fasciculations (Cited in 48 chemicals.) 61 TEC:C10 Peripheral Nerve and Sensation: Paresthesia (Cited in 49 chemicals.) 21 TEC:C15 Peripheral Nerve and Sensation: Recording from afferent nerve (Cited in 17 chemicals.) 270 TEC:C16 Peripheral Nerve and Sensation: Recording from peripheral motor nerve (Cited in 168 chemicals.) 44 TEC:C17 Peripheral Nerve and Sensation: Local anesthetic (Cited in 29 chemicals.) 139 TEC:C18 Peripheral Nerve and Sensation: Structural change in nerve or sheath (Cited in 76 chemicals.) 4 TEC:C60 Peripheral Nerve and Sensation: Peripheral nerve tumors (Cited in 4 chemicals.) 23 TEC:D01 Olfaction: Deviated nasal septum (Cited in 14 chemicals.) 23 TEC:D02 Olfaction: Ulcerated nasal septum (Cited in 18 chemicals.) 19 TEC:D03 Olfaction: Change in olfactory nerve (Cited in 14 chemicals.) 39 TEC:D04 Olfaction: Change in sensation of smell (Cited in 26 chemicals.) 552 TEC:D07 Olfaction: Other olfaction effects (Cited in 324 chemicals.) 192 TEC:D09 Olfaction: Tumors (Cited in 61 chemicals.) 22 TEC:D10 Eye: Optic nerve neuropathy (Cited in 19 chemicals.) 1 TEC:D11 Eye: Cycloplegia (Cited in 1 chemicals.) 4 TEC:D12 Eye: Changes in refraction (Cited in 3 chemicals.) 1 TEC:D13 Eye: Ciliary spasm (Cited in 1 chemicals.) 53 TEC:D14 Eye: Visual field changes (Cited in 42 chemicals.) 156 TEC:D15 Eye: Miosis (pupilliary constriction) (Cited in 82 chemicals.) 167 TEC:D16 Eye: Mydriasis (pupilliary dilation) (Cited in 103 chemicals.) 552 TEC:D17 Eye: Lacrimation (Cited in 338 chemicals.) 53 TEC:D18 Eye: Chromodacryorrhea (Cited in 46 chemicals.) 10 TEC:D19 Eye: Increased intraocular pressure (Cited in 8 chemicals.) 51 TEC:D20 Eye: Retinal changes pigmentary deposition, retinitis, other) (Cited in 40 chemicals.) 17 TEC:D21 Eye: Hemorrhage (Cited in 13 chemicals.) 10 TEC:D22 Eye: Changes in circulation (Cited in 9 chemicals.) 11 TEC:D23 Eye: Diplopia (Cited in 11 chemicals.) 14 TEC:D24 Eye: Change in extra- ocular muscles (Cited in 12 chemicals.) 459 TEC:D25 Eye: Conjunctiva irritation (Cited in 283 chemicals.) 126 TEC:D26 Eye: Corneal damage (Cited in 94 chemicals.) 15 TEC:D27 Eye: Iritis (Cited in 13 chemicals.) 130 TEC:D28 Eye: Ptosis (Cited in 95 chemicals.) 16 TEC:D29 Eye: Tumors (Cited in 10 chemicals.) 476 TEC:D35 Eye: Other eye effects (Cited in 357 chemicals.) 66 TEC:D40 Ear: Change in acuity (Cited in 39 chemicals.) 17 TEC:D41 Ear: Tinnitus (Cited in 12 chemicals.) 35 TEC:D43 Ear: Changes in vestibular functions (Cited in 16 chemicals.) 62 TEC:D44 Ear: Change in cochlear structure or function (Cited in 32 chemicals.) 74 TEC:D45 Ear: Tumors (Cited in 49 chemicals.) 13 TEC:D50 Taste: Change in function (Cited in 13 chemicals.) 39 TEC:E01 Autonomic Nervous System: Sympathomimetic (Cited in 34 chemicals.) 1 TEC:E02 Autonomic Nervous System: Alpha adrenergic blocker (Cited in 1 chemicals.) 7 TEC:E03 Autonomic Nervous System: Beta adrenergic blocker (Cited in 4 chemicals.) 9 TEC:E04 Autonomic Nervous System: Central sympatholytic (Cited in 4 chemicals.) 7 TEC:E05 Autonomic Nervous System: Ganglion blocker (Cited in 7 chemicals.) 1 TEC:E06 Autonomic Nervous System: Ganglion facilitant (Cited in 1 chemicals.) 144 TEC:E08 Autonomic Nervous System: Other (direct) parasympathomimetic (Cited in 87 chemicals.) 1 TEC:E09 Autonomic Nervous System: Intensity beta adrenergic effects (Cited in 1 chemicals.) 21 TEC:E15 Autonomic Nervous System: Smooth muscle relaxant (mechanism undefined, spasmolytic) (Cited in 18 chemicals.) 20 TEC:E16 Autonomic Nervous System: Parasympatholytic (Cited in 17 chemicals.) 658 TEC:F01 Behavioral: General anesthetic (Cited in 355 chemicals.) 166 TEC:F02 Behavioral: Anticonvulsant (Cited in 74 chemicals.) 43 TEC:F03 Behavioral: Wakefulness (Cited in 32 chemicals.) 230 TEC:F04 Behavioral: Sleep (Cited in 168 chemicals.) 574 TEC:F05 Behavioral: Altered sleep time (including change in righting reflex) (Cited in 361 chemicals.) 37 TEC:F06 Behavioral: Euphoria (Cited in 28 chemicals.) 3,763 TEC:F07 Behavioral: Somnolence (general depressed activity) (Cited in 1,865 chemicals.) 201 TEC:F08 Behavioral: Hallucinations, distorted perceptions (Cited in 152 chemicals.) 15 TEC:F09 Behavioral: Changes in REM sleep (human) (Cited in 13 chemicals.) 74 TEC:F10 Behavioral: Toxic psychosis (Cited in 56 chemicals.) 1,159 TEC:F11 Behavioral: Tremor (Cited in 663 chemicals.) 3,250 TEC:F12 Behavioral: Convulsions or effect on seizure threshold (Cited in 1,350 chemicals.) 904 TEC:F13 Behavioral: Excitement (Cited in 522 chemicals.) 62 TEC:F14 Behavioral: Anorexia (human) (Cited in 54 chemicals.) 1,045 TEC:F15 Behavioral: Food intake (animal) (Cited in 644 chemicals.) 283 TEC:F16 Behavioral: Fluid intake (Cited in 181 chemicals.) 1,338 TEC:F17 Behavioral: Change in motor activity (specific assay) (Cited in 607 chemicals.) 1,024 TEC:F18 Behavioral: Muscle weakness (Cited in 587 chemicals.) 1,891 TEC:F19 Behavioral: Ataxia (Cited in 967 chemicals.) 27 TEC:F20 Behavioral: Stiffness (Cited in 25 chemicals.) 194 TEC:F21 Behavioral: Rigidity (includes catalepsy) (Cited in 97 chemicals.) 270 TEC:F22 Behavioral: Tetany (Cited in 119 chemicals.) 489 TEC:F23 Behavioral: Muscle contraction or spasticity (Cited in 328 chemicals.) 684 TEC:F24 Behavioral: Coma (Cited in 382 chemicals.) 143 TEC:F25 Behavioral: Antipsychotic (Cited in 91 chemicals.) 161 TEC:F26 Behavioral: Antianxiety (Cited in 67 chemicals.) 167 TEC:F27 Behavioral: Headache (Cited in 129 chemicals.) 511 TEC:F29 Behavioral: Analgesia (Cited in 179 chemicals.) 111 TEC:F30 Behavioral: Tolerance (Cited in 45 chemicals.) 86 TEC:F31 Behavioral: Withdrawal (Cited in 39 chemicals.) 42 TEC:F32 Behavioral: Abuse (Cited in 21 chemicals.) 174 TEC:F33 Behavioral: Irritability (Cited in 140 chemicals.) 14 TEC:F34 Behavioral: Straub Tail (Cited in 12 chemicals.) 734 TEC:F40 Behavioral: Alteration of classical conditioning (Cited in 370 chemicals.) 378 TEC:F41 Behavioral: Alteration of operant conditioning (Cited in 169 chemicals.) 708 TEC:F42 Behavioral: Change in psychophysiological tests (Cited in 238 chemicals.) 100 TEC:F43 Behavioral: Aggression (Cited in 66 chemicals.) 165 TEC:G01 Cardiac: Cardiomyopathy including infarction (Cited in 111 chemicals.) 31 TEC:G02 Cardiac: Changes in coronary arteries (Cited in 27 chemicals.) 5 TEC:G03 Cardiac: Pericarditis (Cited in 5 chemicals.) 241 TEC:G04 Cardiac: Arrythmias (indlucing changes in conduction) (Cited in 139 chemicals.) 4 TEC:G05 Cardiac: Cardiomegaly (Cited in 4 chemicals.) 264 TEC:G06 Cardiac: EKG changes not diagnostic of above (Cited in 149 chemicals.) 242 TEC:G07 Cardiac: Pulse rate increased without fall in BP (Cited in 164 chemicals.) 223 TEC:G08 Cardiac: Pulse rate decreased with fall in BP (Cited in 144 chemicals.) 42 TEC:G09 Cardiac: Change in force of contraction (Cited in 30 chemicals.) 336 TEC:G10 Cardiac: Change in rate (Cited in 185 chemicals.) 7 TEC:G11 Cardiac: Change in conduction velocity (Cited in 7 chemicals.) 49 TEC:G12 Cardiac: Cardiac output (Cited in 40 chemicals.) 10 TEC:G13 Cardiac: Change in resting or action potential (Cited in 10 chemicals.) 666 TEC:G30 Cardiac: Other changes (Cited in 407 chemicals.) 13 TEC:G60 Cardiac: Tumors (Cited in 9 chemicals.) 178 TEC:G70 Cardiac: Changes in heart weight (Cited in 141 chemicals.) 361 TEC:H01 Vascular: BP elevation not characterized in autonomic section (Cited in 192 chemicals.) 664 TEC:H02 Vascular: BP lowering not characterized in autonomic section (Cited in 327 chemicals.) 5 TEC:H03 Vascular: Pulse pressure increase (Cited in 5 chemicals.) 52 TEC:H04 Vascular: Regional or general arteriolar constriction (Cited in 40 chemicals.) 125 TEC:H05 Vascular: Regional or general arteriolar or venous dilation (Cited in 88 chemicals.) 136 TEC:H06 Vascular: Measurement of regional blood flow (Cited in 80 chemicals.) 6 TEC:H07 Vascular: Change in plasma or blood volume (Cited in 6 chemicals.) 29 TEC:H08 Vascular: Shock (Cited in 28 chemicals.) 11 TEC:H15 Vascular: Acute arterial occulsion (Cited in 7 chemicals.) 112 TEC:H16 Vascular: Structural changes in vessels (Cited in 78 chemicals.) 21 TEC:H17 Vascular: Thromobosis distant from injection site (Cited in 19 chemicals.) 11 TEC:H20 Vascular: Contraction (isolated tissue) (Cited in 8 chemicals.) 13 TEC:H21 Vascular: Relaxation (isolated tissue) (Cited in 12 chemicals.) 291 TEC:H30 Vascular: Other changes (Cited in 199 chemicals.) 1 TEC:H35 Vascular: Effect on gills and gill functions (Cited in 1 chemicals.) 62 TEC:H60 Vascular: Tumors (Cited in 37 chemicals.) 5 TEC:J01 Lung, Thorax, or Respiration: Ciliary function changes (Cited in 4 chemicals.) 438 TEC:J02 Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi (Cited in 265 chemicals.) 18 TEC:J03 Lung, Thorax, or Respiration: Bronchiolar dilation (Cited in 15 chemicals.) 50 TEC:J04 Lung, Thorax, or Respiration: Bronchiolar constriction, including asthma (Cited in 38 chemicals.) 11 TEC:J05 Lung, Thorax, or Respiration: Bronchiectasis (Cited in 6 chemicals.) 151 TEC:J06 Lung, Thorax, or Respiration: Emphysema (Cited in 101 chemicals.) 123 TEC:J07 Lung, Thorax, or Respiration: Changes in pulmonary vascular resistance (Cited in 74 chemicals.) 15 TEC:J08 Lung, Thorax, or Respiration: Consolidation (Cited in 13 chemicals.) 158 TEC:J12 Lung, Thorax, or Respiration: Fibrosis, focal (pneumoconiosis) (Cited in 106 chemicals.) 130 TEC:J13 Lung, Thorax, or Respiration: Fibrosis (interstitial) (Cited in 82 chemicals.) 46 TEC:J14 Lung, Thorax, or Respiration: Fibrosing alveolitis (Cited in 31 chemicals.) 672 TEC:J15 Lung, Thorax, or Respiration: Acute pulmonary edema (Cited in 388 chemicals.) 185 TEC:J16 Lung, Thorax, or Respiration: Chronic pulmonary edema or congestion (Cited in 138 chemicals.) 25 TEC:J17 Lung, Thorax, or Respiration: Pleural effusion (Cited in 22 chemicals.) 16 TEC:J18 Lung, Thorax, or Respiration: Pleural thickening (Cited in 11 chemicals.) 101 TEC:J20 Lung, Thorax, or Respiration: Respiratory obstruction (Cited in 71 chemicals.) 232 TEC:J21 Lung, Thorax, or Respiration: Cough (Cited in 146 chemicals.) 1,988 TEC:J22 Lung, Thorax, or Respiration: Dyspnea (Cited in 1,136 chemicals.) 46 TEC:J23 Lung, Thorax, or Respiration: Sputum (Cited in 30 chemicals.) 499 TEC:J24 Lung, Thorax, or Respiration: Cyanosis (Cited in 332 chemicals.) 1,182 TEC:J25 Lung, Thorax, or Respiration: Respiratory depression (Cited in 633 chemicals.) 618 TEC:J26 Lung, Thorax, or Respiration: Respiratory stimulation (Cited in 348 chemicals.) 33 TEC:J27 Lung, Thorax, or Respiration: Pulmonary emboli (Cited in 25 chemicals.) 2,282 TEC:J30 Lung, Thorax, or Respiration: Other changes (Cited in 1,109 chemicals.) 1,049 TEC:J60 Lung, Thorax, or Respiration: Tumors (Cited in 448 chemicals.) 65 TEC:J61 Lung, Thorax, or Respiration: Bronchogenic carcinoma (Cited in 53 chemicals.) 289 TEC:J70 Lung, Thorax, or Respiration: Changes in lung weight (Cited in 187 chemicals.) 794 TEC:K01 Gastrointestinal: Changes in structure or function of salivary glands (Cited in 443 chemicals.) 101 TEC:K02 Gastrointestinal: Changes in structure or function of exocrine pancreas (Cited in 62 chemicals.) 27 TEC:K03 Gastrointestinal: Changes in structure or function of esophagus (Cited in 24 chemicals.) 85 TEC:K04 Gastrointestinal: Alteration in gastric secretion (Cited in 62 chemicals.) 82 TEC:K05 Gastrointestinal: Gastritis (Cited in 65 chemicals.) 242 TEC:K06 Gastrointestinal: Ulceration or bleeding from stomach (Cited in 145 chemicals.) 26 TEC:K07 Gastrointestinal: Ulceration or bleeding from duodeum (Cited in 21 chemicals.) 75 TEC:K08 Gastrointestinal: Ulceration or bleeding from small intestine (Cited in 48 chemicals.) 42 TEC:K09 Gastrointestinal: Ulceration or bleeding from large intestine (Cited in 30 chemicals.) 1,243 TEC:K12 Gastrointestinal: Hypermotility, diarrhea (Cited in 734 chemicals.) 1,019 TEC:K13 Gastrointestinal: Nausea or vomiting (Cited in 572 chemicals.) 88 TEC:K14 Gastrointestinal: Decreased motility or constipation (Cited in 59 chemicals.) 6 TEC:K15 Gastrointestinal: Malabsorption (Cited in 6 chemicals.) 72 TEC:K17 Gastrointestinal: Peritonitis (Cited in 49 chemicals.) 68 TEC:K20 Gastrointestinal: Necrotic changes (Cited in 51 chemicals.) 996 TEC:K30 Gastrointestinal: Other changes (Cited in 650 chemicals.) 10 TEC:K31 Gastrointestinal: Contraction (isolated tissue) (Cited in 7 chemicals.) 1 TEC:K32 Gastrointestinal: Relaxation (isolated tissue) (Cited in 1 chemicals.) 579 TEC:K60 Gastrointestinal: Tumors (Cited in 224 chemicals.) 103 TEC:K61 Gastrointestinal: Colon tumors (Cited in 40 chemicals.) 11 TEC:K70 Gastrointestinal: Changes in pancreatic weight (Cited in 10 chemicals.) 277 TEC:L01 Liver: Hepatitis (hepatocellular necrosis), diffuse (Cited in 173 chemicals.) 356 TEC:L02 Liver: Hepatitis (hepatocellular necrosis), zonal (Cited in 174 chemicals.) 479 TEC:L03 Liver: Fatty liver degeneration (Cited in 264 chemicals.) 81 TEC:L04 Liver: Hepatitis, fibrous (cirrhosis, post- necrotic scarring) (Cited in 37 chemicals.) 27 TEC:L11 Liver: Jaundice, cholestatic (Cited in 23 chemicals.) 58 TEC:L12 Liver: Jaundice, other or unclassified (Cited in 44 chemicals.) 524 TEC:L14 Liver: Liver function tests impaired (Cited in 305 chemicals.) 53 TEC:L15 Liver: Change in gall bladder structure or function (Cited in 44 chemicals.) 8 TEC:L19 Liver: Jaundice (or hyperbilirubinemia) hepatocellular (Cited in 8 chemicals.) 3,620 TEC:L30 Liver: Other changes (Cited in 1,307 chemicals.) 109 TEC:L50 Liver: Multiple effects (Cited in 82 chemicals.) 1,525 TEC:L60 Liver: Tumors (Cited in 500 chemicals.) 41 TEC:L61 Liver: Angiosarcoma (Cited in 22 chemicals.) 2,277 TEC:L70 Liver: Changes in liver weight (Cited in 925 chemicals.) 81 TEC:M01 Kidney, Ureter, and Bladder: Changes in blood vessels or in circulation of kidney (Cited in 55 chemicals.) 57 TEC:M02 Kidney, Ureter, and Bladder: Changes primarily in glomeruli (Cited in 48 chemicals.) 1,068 TEC:M03 Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) (Cited in 534 chemicals.) 134 TEC:M04 Kidney, Ureter, and Bladder: Changes in both tubules and glomeruli (Cited in 98 chemicals.) 85 TEC:M05 Kidney, Ureter, and Bladder: Interstitial nephritis (Cited in 71 chemicals.) 272 TEC:M10 Kidney, Ureter, and Bladder: Urine volume increased (Cited in 191 chemicals.) 144 TEC:M11 Kidney, Ureter, and Bladder: Urine volume decreased or anuria (Cited in 119 chemicals.) 218 TEC:M12 Kidney, Ureter, and Bladder: Renal function tests depressed (Cited in 126 chemicals.) 207 TEC:M13 Kidney, Ureter, and Bladder: Proteinuria (Cited in 138 chemicals.) 168 TEC:M14 Kidney, Ureter, and Bladder: Hematuria (Cited in 105 chemicals.) 744 TEC:M16 Kidney, Ureter, and Bladder: Other changes in urine composition (Cited in 475 chemicals.) 37 TEC:M20 Kidney, Ureter, and Bladder: Inflammation, necrosis or scarring of bladder (Cited in 28 chemicals.) 9 TEC:M21 Kidney, Ureter, and Bladder: Structural or functional change in ureter (Cited in 8 chemicals.) 22 TEC:M29 Kidney, Ureter, and Bladder: Incontinence (Cited in 18 chemicals.) 1,455 TEC:M30 Kidney, Ureter, and Bladder: Other changes (Cited in 734 chemicals.) 328 TEC:M60 Kidney, Ureter, and Bladder: Bladder tumors (Cited in 125 chemicals.) 331 TEC:M61 Kidney, Ureter, and Bladder: Kidney tumors (Cited in 155 chemicals.) 504 TEC:M70 Kidney, Ureter, and Bladder: Changes in bladder weight (Cited in 358 chemicals.) 400 TEC:M71 Kidney, Ureter, and Bladder: Changes in kidney weight (Cited in 222 chemicals.) 7 TEC:N01 Endocrine: Antidiuresis (Cited in 5 chemicals.) 153 TEC:N02 Endocrine: Change in LH (Cited in 92 chemicals.) 22 TEC:N03 Endocrine: Change in GH (Cited in 15 chemicals.) 126 TEC:N04 Endocrine: Change in gonadotropins (Cited in 72 chemicals.) 40 TEC:N05 Endocrine: Thyroid weight (goiter) (Cited in 31 chemicals.) 8 TEC:N06 Endocrine: Toxic goiter- hypofunction (Cited in 7 chemicals.) 73 TEC:N07 Endocrine: Evidence of thyroid hyperfunction (Cited in 50 chemicals.) 231 TEC:N08 Endocrine: Evidence of thyroid hypofunction (Cited in 118 chemicals.) 3 TEC:N10 Endocrine: Hyperparathyroidism (Cited in 3 chemicals.) 50 TEC:N12 Endocrine: Adrenal cortex hyperplasia (Cited in 35 chemicals.) 45 TEC:N13 Endocrine: Adrenal cortex hypoplasia (Cited in 22 chemicals.) 6 TEC:N15 Endocrine: Aldosteronism (Cited in 5 chemicals.) 146 TEC:N16 Endocrine: Androgenic (Cited in 82 chemicals.) 191 TEC:N17 Endocrine: Estrogenic (Cited in 91 chemicals.) 63 TEC:N18 Endocrine: Differential effect of sex or castration on observed toxicity (Cited in 43 chemicals.) 92 TEC:N19 Endocrine: Effect on menstrual cycle (Cited in 61 chemicals.) 3 TEC:N20 Endocrine: Gynecomastia (Cited in 3 chemicals.) 72 TEC:N21 Endocrine: Diabetes mellitus (Cited in 9 chemicals.) 138 TEC:N22 Endocrine: Hypoglycemia (Cited in 96 chemicals.) 1 TEC:N23 Endocrine: Ketosis (Cited in 1 chemicals.) 192 TEC:N24 Endocrine: Hyperglycemia (Cited in 125 chemicals.) 3 TEC:N25 Endocrine: Diabetes insipidus (nephrogenic or CNS) (Cited in 3 chemicals.) 829 TEC:N30 Endocrine: Other changes (Cited in 431 chemicals.) 177 TEC:N60 Endocrine: Tumors (Cited in 122 chemicals.) 69 TEC:N61 Endocrine: Adrenal cortex tumors (Cited in 49 chemicals.) 186 TEC:N62 Endocrine: Thyroid tumors (Cited in 92 chemicals.) 10 TEC:N70 Endocrine: Changes in endocrine weight (unspecified) (Cited in 7 chemicals.) 53 TEC:N71 Endocrine: Changes in pituitary weight (Cited in 34 chemicals.) 239 TEC:N72 Endocrine: Changes in adrenal weight (Cited in 177 chemicals.) 545 TEC:N73 Endocrine: Changes in spleen weight (Cited in 341 chemicals.) 419 TEC:N74 Endocrine: Changes in thymus weight (Cited in 226 chemicals.) 177 TEC:N75 Endocrine: Changes in thyroid weight (Cited in 111 chemicals.) 536 TEC:P01 Blood: Hemorrhage (Cited in 357 chemicals.) 170 TEC:P02 Blood: Change in clotting factors (Cited in 102 chemicals.) 435 TEC:P05 Blood: Normocytic anemia (Cited in 288 chemicals.) 21 TEC:P06 Blood: Microcytosis with or without anemia (Cited in 16 chemicals.) 14 TEC:P07 Blood: Macrocytosis (Cited in 9 chemicals.) 291 TEC:P08 Blood: Pigmented or nucleated red blood cells (Cited in 245 chemicals.) 25 TEC:P13 Blood: Granulocytopenia (Cited in 20 chemicals.) 226 TEC:P14 Blood: Luekopenia (Cited in 120 chemicals.) 64 TEC:P15 Blood: Angranulocytosis (Cited in 45 chemicals.) 48 TEC:P16 Blood: Eosinophilia (Cited in 36 chemicals.) 105 TEC:P17 Blood: Thrombocytopenia (Cited in 69 chemicals.) 111 TEC:P20 Blood: Changes in cell count (unspecified) (Cited in 95 chemicals.) 6 TEC:P22 Blood: Oxidant related (GPD deficient) anemia (Cited in 6 chemicals.) 100 TEC:P23 Blood: Other hemolysis with or without anemia (Cited in 62 chemicals.) 309 TEC:P24 Blood: Methemoglobinemia- Carboxhemoglobinemia (Cited in 125 chemicals.) 42 TEC:P25 Blood: Aplastic anemia (Cited in 24 chemicals.) 314 TEC:P26 Blood: Changes in bone marrow not included in above (Cited in 180 chemicals.) 547 TEC:P27 Blood: Changes in spleen (Cited in 317 chemicals.) 1,772 TEC:P28 Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) (Cited in 938 chemicals.) 1,056 TEC:P30 Blood: Other changes (Cited in 647 chemicals.) 144 TEC:P60 Blood: Tumors (Cited in 96 chemicals.) 268 TEC:P61 Blood: Leukemia (Cited in 152 chemicals.) 274 TEC:P62 Blood: Lymphoma including Hodgkin's disease (Cited in 174 chemicals.) 240 TEC:P70 Blood: Changes in other cell count (unspecified) (Cited in 197 chemicals.) 611 TEC:P71 Blood: Changes in erythrocyte (RBC) count (Cited in 421 chemicals.) 571 TEC:P72 Blood: Changes in leukocyte (WBC) count (Cited in 390 chemicals.) 97 TEC:P73 Blood: Changes in platelet count (Cited in 75 chemicals.) 51 TEC:Q01 Musculoskeletal: Changes in teeth and supporting structures (Cited in 29 chemicals.) 26 TEC:Q02 Musculoskeletal: Osteoporosis (Cited in 17 chemicals.) 17 TEC:Q10 Musculoskeletal: Osteomalacia (Cited in 12 chemicals.) 49 TEC:Q15 Musculoskeletal: Joints (Cited in 38 chemicals.) 284 TEC:Q30 Musculoskeletal: Other changes (Cited in 183 chemicals.) 88 TEC:Q60 Musculoskeletal: Tumors (Cited in 52 chemicals.) 94 TEC:R01 Skin: After systemic exposure: Dermatitis, allergic (Cited in 67 chemicals.) 61 TEC:R02 Skin: After systemic exposure: Dermatitis, irritative (Cited in 45 chemicals.) 545 TEC:R03 Skin: After systemic exposure: Dermatitis, other (Cited in 409 chemicals.) 11 TEC:R04 Skin: After systemic exposure: Photosensitivity (Cited in 10 chemicals.) 294 TEC:R10 Skin: After topical application: Primary irritation (Cited in 193 chemicals.) 73 TEC:R11 Skin: After topical application: Corrosive (Cited in 58 chemicals.) 113 TEC:R12 Skin: After topical application: Dermatitis, allergic (Cited in 78 chemicals.) 80 TEC:R13 Skin: After topical application: Cutaneous sensitization (experimental) (Cited in 57 chemicals.) 2 TEC:R14 Skin: After topical application: Photosensitivity (Cited in 2 chemicals.) 56 TEC:R20 Skin and Appendages: Other: Sweating (Cited in 52 chemicals.) 632 TEC:R21 Skin and Appendages: Other: Hair (Cited in 430 chemicals.) 12 TEC:R22 Skin and Appendages: Other: Nails (Cited in 10 chemicals.) 49 TEC:R25 Skin and Appendages: Other: Breast (Cited in 32 chemicals.) 12 TEC:R30 Skin and Appendages: Other glands (Cited in 9 chemicals.) 1,020 TEC:R60 Skin and Appendages: Tumors (Cited in 438 chemicals.) 154 TEC:S01 Immunological Including Allergic: Increase in cellular immune response (Cited in 98 chemicals.) 283 TEC:S02 Immunological Including Allergic: Decrease in cellular immune response (Cited in 161 chemicals.) 106 TEC:S03 Immunological Including Allergic: Increase in humoral response (Cited in 76 chemicals.) 229 TEC:S04 Immunological Including Allergic: Decrease in humoral immune response (Cited in 132 chemicals.) 176 TEC:S05 Immunological Including Allergic: Decreased immune response (Cited in 110 chemicals.) 49 TEC:S06 Immunological Including Allergic: Increased immune response (Cited in 46 chemicals.) 30 TEC:S15 Immunological Including Allergic: Anaphylaxis (multiple organ involvement) (Cited in 23 chemicals.) 27 TEC:S16 Immunological Including Allergic: Other immediate (humoral): uticaria, allergic rhinitis, serum sickness (multiple organ involvement) (Cited in 20 chemicals.) 97 TEC:S18 Immunological Including Allergic: Hypersensitivity delayed (multiple organ involvement) (Cited in 60 chemicals.) 57 TEC:S20 Immunological Including Allergic: Autoimmune (multiple organ involvement) (Cited in 25 chemicals.) 40 TEC:S25 Immunological Including Allergic: Uncharacterized (multiple organ involvement) (Cited in 35 chemicals.) 985 TEC:T01 Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count) (Cited in 443 chemicals.) 1,168 TEC:T02 Reproductive: Paternal effects: Testes, epididymis, sperm duct (Cited in 465 chemicals.) 376 TEC:T03 Reproductive: Paternal effects: Prostate, seminal vesicle, Cowper's gland, accessory glands (Cited in 204 chemicals.) 26 TEC:T04 Reproductive: Paternal effects: Impotence (Cited in 21 chemicals.) 12 TEC:T05 Reproductive: Paternal effects: Breast development (Cited in 9 chemicals.) 199 TEC:T09 Reproductive: Other effects on male (Cited in 143 chemicals.) 99 TEC:T11 Reproductive: Maternal effects: Oogenesis (Cited in 63 chemicals.) 341 TEC:T12 Reproductive: Maternal effects: Ovaries, fallopian tubes (Cited in 173 chemicals.) 541 TEC:T13 Reproductive: Maternal effects: Uterus, cervix, vagina (Cited in 228 chemicals.) 244 TEC:T14 Reproductive: Maternal effects: Menstrual cycle changes or disorders (Cited in 127 chemicals.) 38 TEC:T15 Reproductive: Maternal effects: Breasts, lactation (prior to or during pregnancy) (Cited in 29 chemicals.) 189 TEC:T16 Reproductive: Maternal effects: Parturition (Cited in 119 chemicals.) 44 TEC:T17 Reproductive: Maternal effects: Postpartum (Cited in 31 chemicals.) 532 TEC:T19 Reproductive: Other effects on female (Cited in 350 chemicals.) 128 TEC:T21 Reproductive: Effects on fertility: Mating performance (e.g., # sperm positive females per # females mated; # copulations per # estrus cycles) (Cited in 84 chemicals.) 273 TEC:T22 Reproductive: Effects on fertility: Female fertility index (e.g., # females pregnant per # sperm positive females; # females pregnant per # females mated) (Cited in 160 chemicals.) 243 TEC:T23 Reproductive: Effects on fertility: Male fertility index (e.g., # males impregnating females per # males exposed to fertile nonpregnant females) (Cited in 140 chemicals.) 485 TEC:T24 Reproductive: Effects on fertility: Pre- implantation mortality (e.g., reduction in number of implants per female; total number of implants per corpora lutea) (Cited in 316 chemicals.) 1,563 TEC:T25 Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants) (Cited in 756 chemicals.) 558 TEC:T26 Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth) (Cited in 340 chemicals.) 241 TEC:T27 Reproductive: Effects on fertility: Abortion (Cited in 140 chemicals.) 453 TEC:T29 Reproductive: Effects on fertility: Other measures of fertility (Cited in 214 chemicals.) 248 TEC:T31 Reproductive: Effects on embryo or fetus: Extra embryonic structures (e.g., placenta, umbilical cord) (Cited in 185 chemicals.) 21 TEC:T32 Reproductive: Effects on embryo or fetus: Maternal- fetal exchange (Cited in 20 chemicals.) 144 TEC:T33 Reproductive: Effects on embryo or fetus: Cytological changes (including somatic cell genetic material) (Cited in 96 chemicals.) 2,112 TEC:T34 Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) (Cited in 905 chemicals.) 1,076 TEC:T35 Reproductive: Effects on embryo or fetus: Fetal death (Cited in 565 chemicals.) 258 TEC:T39 Reproductive: Other effects to embryo or fetus (Cited in 175 chemicals.) 853 TEC:T41 Reproductive: Specific developmental abnormalities: Central nervous system (Cited in 374 chemicals.) 375 TEC:T42 Reproductive: Specific developmental abnormalities: Eye, ear (Cited in 216 chemicals.) 762 TEC:T43 Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue) (Cited in 345 chemicals.) 63 TEC:T44 Reproductive: Specific developmental abnormalities: Skin and skin appendages (Cited in 50 chemicals.) 136 TEC:T45 Reproductive: Specific developmental abnormalities: Body wall (Cited in 97 chemicals.) 1,582 TEC:T46 Reproductive: Specific developmental abnormalities: Musculoskeletal system (Cited in 716 chemicals.) 279 TEC:T47 Reproductive: Specific developmental abnormalities: Cardiovascular (circulatory) system (Cited in 161 chemicals.) 127 TEC:T48 Reproductive: Specific developmental abnormalities: Blood and lymphatic systems (including spleen and marrow) (Cited in 85 chemicals.) 104 TEC:T49 Reproductive: Specific developmental abnormalities: Respiratory system (Cited in 64 chemicals.) 70 TEC:T50 Reproductive: Specific developmental abnormalities: Gastrointestinal system (Cited in 60 chemicals.) 180 TEC:T51 Reproductive: Specific developmental abnormalities: Hepatobiliary system (Cited in 126 chemicals.) 241 TEC:T52 Reproductive: Specific developmental abnormalities: Endocrine system (Cited in 107 chemicals.) 808 TEC:T53 Reproductive: Specific developmental abnormalities: Urogenital system (Cited in 339 chemicals.) 72 TEC:T54 Reproductive: Specific developmental abnormalities: Immune and reticuloendothelial system (Cited in 42 chemicals.) 93 TEC:T55 Reproductive: Specific developmental abnormalities: Homeostasis (Cited in 75 chemicals.) 406 TEC:T59 Reproductive: Other developmental abnormalities (Cited in 249 chemicals.) 76 TEC:T61 Reproductive: Tumorigenic effects: Testicular tumors (Cited in 56 chemicals.) 10 TEC:T62 Reproductive: Tumorigenic effects: Prostate tumors (Cited in 8 chemicals.) 57 TEC:T63 Reproductive: Tumorigenic effects: Ovarian tumors (Cited in 37 chemicals.) 104 TEC:T64 Reproductive: Tumorigenic effects: Uterine tumors (Cited in 66 chemicals.) 176 TEC:T65 Reproductive: Tumorigenic effects: Transplacental tumorigenesis (Cited in 61 chemicals.) 65 TEC:T69 Reproductive: Other reproductive system tumors (Cited in 46 chemicals.) 205 TEC:T71 Reproductive: Effects on newborn: Stillbirth (Cited in 156 chemicals.) 391 TEC:T72 Reproductive: Effects on newborn: Live birth index (Litter size (e.g., # fetuses per litter; measured after birth) (Cited in 252 chemicals.) 62 TEC:T73 Reproductive: Effects on newborn: Sex ratio (Cited in 53 chemicals.) 26 TEC:T74 Reproductive: Effects on newborn: Apgar score (human only) (Cited in 23 chemicals.) 371 TEC:T75 Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive) (Cited in 254 chemicals.) 233 TEC:T76 Reproductive: Effects on newborn: Weaning or lactation index (e.g., # alive at weaning per # alive at day 4) (Cited in 180 chemicals.) 140 TEC:T77 Reproductive: Effects on newborn: Other neonatal measures or effects (Cited in 104 chemicals.) 1,140 TEC:T81 Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain) (Cited in 547 chemicals.) 47 TEC:T82 Reproductive: Effects on newborn: Germ cell effects (in offspring) (Cited in 33 chemicals.) 510 TEC:T83 Reproductive: Effects on newborn: Biochemical and metabolic (Cited in 229 chemicals.) 11 TEC:T84 Reproductive: Effects on newborn: Drug dependence (Cited in 9 chemicals.) 672 TEC:T85 Reproductive: Effects on newborn: Behavioral (Cited in 316 chemicals.) 341 TEC:T86 Reproductive: Effects on newborn: Physical (Cited in 190 chemicals.) 263 TEC:T87 Reproductive: Effects on newborn: Other postnatal measures or effects (Cited in 151 chemicals.) 332 TEC:T91 Reproductive: Effects on newborn: Delayed effects (Cited in 151 chemicals.) 4,608 TEC:U01 Nutritional and Gross Metabolic: Weight loss or decreased weight gain (Cited in 1,775 chemicals.) 44 TEC:U02 Nutritional and Gross Metabolic: Conditioned vitamin deficiency (Cited in 38 chemicals.) 41 TEC:U03 Nutritional and Gross Metabolic: Dehydration (Cited in 30 chemicals.) 91 TEC:U05 Nutritional and Gross Metabolic: Changes in: Na (Cited in 72 chemicals.) 29 TEC:U06 Nutritional and Gross Metabolic: Changes in: Cl (Cited in 28 chemicals.) 152 TEC:U07 Nutritional and Gross Metabolic: Changes in: Ca (Cited in 97 chemicals.) 48 TEC:U08 Nutritional and Gross Metabolic: Changes in: P (Cited in 41 chemicals.) 52 TEC:U09 Nutritional and Gross Metabolic: Changes in: Fe (Cited in 38 chemicals.) 73 TEC:U10 Nutritional and Gross Metabolic: Changes in: K (Cited in 55 chemicals.) 109 TEC:U11 Nutritional and Gross Metabolic: Changes in: Other metals (Cited in 61 chemicals.) 72 TEC:U20 Nutritional and Gross Metabolic: Changes in: Metabolic acidosis (Cited in 57 chemicals.) 8 TEC:U21 Nutritional and Gross Metabolic: Changes in: Metabolic alkalosis (Cited in 8 chemicals.) 285 TEC:U25 Nutritional and Gross Metabolic: Body temperature increase (Cited in 186 chemicals.) 567 TEC:U28 Nutritional and Gross Metabolic: Body temperature decrease (Cited in 330 chemicals.) 134 TEC:U30 Nutritional and Gross Metabolic: Other changes (Cited in 112 chemicals.) 2,317 TEC:V01 Tumorigenic: Carcinogenic by RTECS criteria (Cited in 646 chemicals.) 1,044 TEC:V02 Tumorigenic: Neoplastic by RTECS criteria (Cited in 523 chemicals.) 2,111 TEC:V03 Tumorigenic: Equivocal tumorigenic agent by RTECS criteria (Cited in 858 chemicals.) 28 TEC:V05 Tumorigenic: Cells (cultured) transformed (Cited in 20 chemicals.) 152 TEC:V08 Tumorigenic: Increased incidence of tumors in susceptible strains (Cited in 61 chemicals.) 736 TEC:V10 Tumorigenic: Tumors at site of application (Cited in 336 chemicals.) 70 TEC:V15 Tumorigenic: Tumor types after systemic administration not seen spontaneously (Cited in 44 chemicals.) 131 TEC:V16 Tumorigenic: Facilitates action of known carcinogens (Cited in 85 chemicals.) 144 TEC:V25 Tumorigenic: Protects against induction of experimental tumors (Cited in 77 chemicals.) 428 TEC:V30 Tumorigenic: Active as anti-cancer agent (Cited in 210 chemicals.) 968 TEC:Y01 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase (Cited in 348 chemicals.) 119 TEC:Y02 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other esterases (Cited in 73 chemicals.) 515 TEC:Y03 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases (Cited in 374 chemicals.) 98 TEC:Y04 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other hydrolases (Cited in 65 chemicals.) 7 TEC:Y05 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cabonic anhydrase (Cited in 7 chemicals.) 9 TEC:Y06 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Xanthine oxidases (Cited in 8 chemicals.) 569 TEC:Y07 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (Cited in 271 chemicals.) 23 TEC:Y08 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Monoamine oxidase (Cited in 22 chemicals.) 201 TEC:Y09 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation) (Cited in 123 chemicals.) 321 TEC:Y10 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases (Cited in 233 chemicals.) 154 TEC:Y11 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Catalases (Cited in 111 chemicals.) 331 TEC:Y12 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases (Cited in 206 chemicals.) 28 TEC:Y13 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphokinase (Cited in 22 chemicals.) 2 TEC:Y14 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hexokinases (Cited in 2 chemicals.) 736 TEC:Y15 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases (Cited in 407 chemicals.) 267 TEC:Y16 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other transferases (Cited in 179 chemicals.) 48 TEC:Y17 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Peptidases (Cited in 44 chemicals.) 16 TEC:Y18 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Proteases (Cited in 15 chemicals.) 13 TEC:Y19 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Isomerases (Cited in 12 chemicals.) 627 TEC:Y20 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects (Cited in 327 chemicals.) 347 TEC:Y21 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymes (Cited in 234 chemicals.) 17 TEC:Y23 Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Reactivates cholinesterase (Cited in 9 chemicals.) 6 TEC:Y25 Biochemical: Effect on specific coenzyme: B vitamins including folate (Cited in 6 chemicals.) 13 TEC:Y26 Biochemical: Effect on specific coenzyme: CoA (Cited in 10 chemicals.) 10 TEC:Y27 Biochemical: Effect on specific coenzyme: NAD, NADP (Cited in 9 chemicals.) 5 TEC:Y28 Biochemical: Effect on specific coenzyme: Other coenzymes (Cited in 5 chemicals.) 7 TEC:Y29 Biochemical: Effect on specific coenzyme: Proportion of isoenzymes (Cited in 7 chemicals.) 3 TEC:Y30 Biochemical: Effect on specific coenzyme: Disturbed regulation (Cited in 3 chemicals.) 18 TEC:Y35 Biochemical: Metabolism (intermediary): Xanthine, purine or nucleotides including urate (Cited in 13 chemicals.) 54 TEC:Y36 Biochemical: Metabolism (intermediary): Porphyrin including bile pigments (Cited in 33 chemicals.) 619 TEC:Y37 Biochemical: Metabolism (intermediary): Lipids including transport (Cited in 293 chemicals.) 55 TEC:Y38 Biochemical: Metabolism (intermediary): Amino acids (including renal excretion) (Cited in 47 chemicals.) 95 TEC:Y39 Biochemical: Metabolism (intermediary): Plasma proteins not involving coagulation (Cited in 73 chemicals.) 763 TEC:Y40 Biochemical: Metabolism (intermediary): Other proteins (Cited in 382 chemicals.) 29 TEC:Y41 Biochemical: Metabolism (intermediary): Glycolytic (Cited in 27 chemicals.) 3 TEC:Y42 Biochemical: Metabolism (intermediary): TCS cycle (Cited in 3 chemicals.) 26 TEC:Y44 Biochemical: Metabolism (intermediary): Other carbohydrates (Cited in 25 chemicals.) 26 TEC:Y45 Biochemical: Metabolism (intermediary): Histamines (including liberation not immunochemical in origin) (Cited in 19 chemicals.) 68 TEC:Y50 Biochemical: Metabolism (intermediary): Effect on mitochondrial function (Cited in 53 chemicals.) 7 TEC:Y51 Biochemical: Metabolism (intermediary): Effect on active transport (Cited in 6 chemicals.) 16 TEC:Y52 Biochemical: Metabolism (intermediary): Effect on Na-K pump (Cited in 13 chemicals.) 578 TEC:Y53 Biochemical: Metabolism (intermediary): Other (Cited in 286 chemicals.) 45 TEC:Y54 Biochemical: Metabolism (intermediary): Effect on cyclic nucleotides (Cited in 38 chemicals.) 925 TEC:Y55 Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation (Cited in 362 chemicals.) 13 TEC:Y60 Biochemical: Neurotransmitters or modulators (putative): Catecholamine levels in sympathetic nerves (Cited in 12 chemicals.) 93 TEC:Y61 Biochemical: Neurotransmitters or modulators (putative): Catecholamine levels in CNS (Cited in 65 chemicals.) 187 TEC:Y64 Biochemical: Neurotransmitters or modulators (putative): Dopamine in striatum (Cited in 79 chemicals.) 144 TEC:Y65 Biochemical: Neurotransmitters or modulators (putative): Dopamine at other sites (Cited in 84 chemicals.) 2,617 TEC:Z01 Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field (Cited in 1,208 chemicals.) 116 TEC:Z71 Related to Chronic Data: Changes in ovarian weight (Cited in 81 chemicals.) 157 TEC:Z72 Related to Chronic Data: Changes in prostate weight (Cited in 78 chemicals.) 417 TEC:Z73 Related to Chronic Data: Changes in testicular weight (Cited in 233 chemicals.) 293 TEC:Z74 Related to Chronic Data: Changes in uterine weight (Cited in 105 chemicals.)