RTECS:VL0480000 The Registry of Toxic Effects of Chemical Substances

Rosin

RTECS #: VL0480000

CAS #: 8050-09-7

UPDATE: November 2007 MW: N/R MF: N/R

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

ACUTE TOXICITY DATA:

OTHER MULTIPLE DOSE DATA:

REVIEWS:

STANDARDS AND REGULATIONS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

BALS 3A

Bandis G100

EM 3

Highrosin

Hongkong rosin WW

KE 709

Rondis R

Rosin WW

Rosin core solder pyrolysis products (ACGIH)

Shiragiku rosin

Yellow resin

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
inhalation
rat lethal concentration (50 percent kill): 110 mg/m³ Behavioral: Somnolence (general depressed activity)

Cardiac: Pulse rate decreased with fall in BP

Lung, Thorax, or Respiration: Respiratory depression VCVPS* -,294,1998
oral
mouse lethal dose (50 percent kill): 2.2 mg/kg Behavioral: Somnolence (general depressed activity)

Cardiac: Pulse rate decreased with fall in BP

Lung, Thorax, or Respiration: Respiratory depression VCVPS* -,294,1998
oral
rat lethal dose (50 percent kill): 3.0 mg/kg Brain and Coverings: Other degenerative changes

Liver: Other changes

Biochemical: Metabolism (intermediary): Other VCVPS* -,294,1998

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
rat lowest published toxic dose: 175 gm/kg/50 day- intermittent Lung, Thorax, or Respiration: Dyspnea

Liver: Hepatitis (hepatocellular necrosis), zonal

Liver: Fatty liver degeneration VCVPS* -,294,1998
oral
rabbit lowest published toxic dose: 455 gm/kg/13 week- intermittent Liver: Other changes

Blood: Thrombocytopenia

Nutritional and Gross Metabolic: Changes in: K VCVPS* -,294,1998
skin
human lowest published toxic concentration: 20 pph/48 hour- continuous Skin: After topical application: Dermatitis, allergic AJCDE* 13,177,2002
skin
man lowest published toxic concentration: 20 pph/96 hour- continuous Skin: After topical application: Dermatitis, allergic AJCDE* 13,74,2002

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Control as low as possible (sen) DTLVS* TLV/BEI,2007

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - KOREA time-weighted average 0.1 mg/m³, 2006
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.1 mg/m³, 2003
Occupational Exposure Limit - NEW ZEALAND sen, JAN2002
Occupational Exposure Limit - RUSSIA short term exposure limit 4 mg/m³, JUN2003

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X2732;
Number of Industries 1;
Total Number of Facilities 511;
Number of Occupations 1;
Total Number of Employees Exposed 511
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X6806;
Number of Industries 9;
Total Number of Facilities 758;
Number of Occupations 14;
Total Number of Employees Exposed 8,324;
Total Number of Female Employees Exposed 2,339
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80164;
Number of Industries 199;
Total Number of Facilities 27,401;
Number of Occupations 133;
Total Number of Employees Exposed 566,016;
Total Number of Female Employees Exposed 212,612

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY

REFERENCES:
CODEN
REFERENCE

AJCDE* American Journal of Contact Dermatitis: Official Journal of the American Contact Dermatitis Society (Philadelphia, PA : W.B. Saunders, Harcourt Brace Jovanovich) V.1-14 1990-2003.
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
VCVPS* "Vrednie chemichescie veshestva. Prirodnie organicheskie soedinenia" (Hazardous substances. Nature products.) Volkova N.V. et al., Sankt-Peterburg, 1998.

RTECS Compound Description:
Human Data
Natural Product

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SYNONYMS:
BALS 3A Bandis G100 EM 3 Highrosin Hongkong rosin WW KE 709	Rondis R Rosin WW Rosin core solder pyrolysis products (ACGIH) Shiragiku rosin Yellow resin

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST	ROUTE/ ORGANISM/ TISSUE	DOSE	REFERENCE
N/R	N/R	N/R	N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
inhalation rat	lethal concentration (50 percent kill): 110 mg/m³	Behavioral: Somnolence (general depressed activity) Cardiac: Pulse rate decreased with fall in BP Lung, Thorax, or Respiration: Respiratory depression	VCVPS* -,294,1998
oral mouse	lethal dose (50 percent kill): 2.2 mg/kg	Behavioral: Somnolence (general depressed activity) Cardiac: Pulse rate decreased with fall in BP Lung, Thorax, or Respiration: Respiratory depression	VCVPS* -,294,1998
oral rat	lethal dose (50 percent kill): 3.0 mg/kg	Brain and Coverings: Other degenerative changes Liver: Other changes Biochemical: Metabolism (intermediary): Other	VCVPS* -,294,1998

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
oral rat	lowest published toxic dose: 175 gm/kg/50 day- intermittent	Lung, Thorax, or Respiration: Dyspnea Liver: Hepatitis (hepatocellular necrosis), zonal Liver: Fatty liver degeneration	VCVPS* -,294,1998
oral rabbit	lowest published toxic dose: 455 gm/kg/13 week- intermittent	Liver: Other changes Blood: Thrombocytopenia Nutritional and Gross Metabolic: Changes in: K	VCVPS* -,294,1998
skin human	lowest published toxic concentration: 20 pph/48 hour- continuous	Skin: After topical application: Dermatitis, allergic	AJCDE* 13,177,2002
skin man	lowest published toxic concentration: 20 pph/96 hour- continuous	Skin: After topical application: Dermatitis, allergic	AJCDE* 13,74,2002

REVIEWS:
ORGANIZATION	STANDARD	REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value	Control as low as possible (sen)	DTLVS* TLV/BEI,2007

STANDARDS AND REGULATIONS:
ORGANIZATION	STANDARD	REFERENCE
Occupational Exposure Limit - KOREA	time-weighted average 0.1 mg/m³, 2006
Occupational Exposure Limit - THE NETHERLANDS	MAC-TGG 0.1 mg/m³, 2003
Occupational Exposure Limit - NEW ZEALAND	sen, JAN2002
Occupational Exposure Limit - RUSSIA	short term exposure limit 4 mg/m³, JUN2003

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION	STANDARD or SURVEY	REFERENCE
National Occupational Exposure Survey 1983	National Occupational Exposure Survey 1983: Hazard Code: X2732; Number of Industries 1; Total Number of Facilities 511; Number of Occupations 1; Total Number of Employees Exposed 511
National Occupational Exposure Survey 1983	National Occupational Exposure Survey 1983: Hazard Code: X6806; Number of Industries 9; Total Number of Facilities 758; Number of Occupations 14; Total Number of Employees Exposed 8,324; Total Number of Female Employees Exposed 2,339
National Occupational Exposure Survey 1983	National Occupational Exposure Survey 1983: Hazard Code: 80164; Number of Industries 199; Total Number of Facilities 27,401; Number of Occupations 133; Total Number of Employees Exposed 566,016; Total Number of Female Employees Exposed 212,612

STATUS IN FEDERAL AGENCIES:
ORGANIZATION	REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY

REFERENCES:
CODEN	REFERENCE
AJCDE*	American Journal of Contact Dermatitis: Official Journal of the American Contact Dermatitis Society (Philadelphia, PA : W.B. Saunders, Harcourt Brace Jovanovich) V.1-14 1990-2003.
DTLVS*	The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
VCVPS*	"Vrednie chemichescie veshestva. Prirodnie organicheskie soedinenia" (Hazardous substances. Nature products.) Volkova N.V. et al., Sankt-Peterburg, 1998.