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Ricinoleic acid

RTECS #: VJ3150000

CAS #: 141-22-0

UPDATE: August 2007 MW: 298.52 MF: C18H34O3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. TUMORIGENIC DATA:
  4. REVIEWS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. 12 - Hydroxy - cis - 9 - octadecenoic acid
  2. 9 - Octadecenoic acid, 12 - hydroxy - , (Z) -
  3. Acide ricinoleique (French)
  4. Kyselina 12 - hydroxy - 9 - oktadecenova (Czech)
  1. Kyselina ricinolova (Czech)
  2. Oleic acid, 12 - hydroxy -
  3. Ricinic acid
  4. Ricinolic acid


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
guinea pig 		10 mg mild AEPPAE 364,87,2001
eye
guinea pig 		0.9 mg/8 day- intermittent mild AEPPAE 364,87,2001


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
subcutaneous
rabbit 		lowest published toxic dose: 390 mg/kg/17 week- intermittent Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Tumorigenic: Tumors at site of application 		CRSBAW 137,760,1943


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
FCTOD7 44,1689,2006


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83687;
Number of Industries 25;
Total Number of Facilities 1,453;
Number of Occupations 27;
Total Number of Employees Exposed 16,450
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83687;
Number of Industries 2;
Total Number of Facilities 41;
Number of Occupations 3;
Total Number of Employees Exposed 654;
Total Number of Female Employees Exposed 70


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC.
CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849-
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-

RTECS Compound Description:
   Tumorigen
   Natural Product

Click Here for Additional Information about RTECS

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