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| UPDATE: May 2009 | MW: 507.88 | MF: C20H22ClN•2H3O4P |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
|
N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
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N/R
|
N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
intramuscular | guinea pig
lethal dose (50 percent kill): 626 mg/kg
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Behavioral: Somnolence (general depressed activity) | Behavioral: Convulsions or effect on seizure threshold
PSEBAA 80,458,1952
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intramuscular | mouse
lethal dose (50 percent kill): 837 mg/kg
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Behavioral: Somnolence (general depressed activity) | Behavioral: Convulsions or effect on seizure threshold
PSEBAA 80,458,1952
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intravenous | mouse
lethal dose (50 percent kill): 54 mg/kg
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Behavioral: Somnolence (general depressed activity) | Behavioral: Convulsions or effect on seizure threshold
PSEBAA 80,458,1952
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oral | guinea pig
lethal dose (50 percent kill): 993 mg/kg
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Behavioral: Somnolence (general depressed activity) | Behavioral: Convulsions or effect on seizure threshold
PSEBAA 80,458,1952
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oral | mouse
lethal dose (50 percent kill): 1,116 mg/kg
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Behavioral: Somnolence (general depressed activity) | Behavioral: Convulsions or effect on seizure threshold
PSEBAA 80,458,1952
|
subcutaneous | guinea pig
lethal dose (50 percent kill): 1,241 mg/kg
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Behavioral: Somnolence (general depressed activity) | Behavioral: Convulsions or effect on seizure threshold
PSEBAA 80,458,1952
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subcutaneous | mouse
lethal dose (50 percent kill): 1,270 mg/kg
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Behavioral: Somnolence (general depressed activity) | Behavioral: Convulsions or effect on seizure threshold
PSEBAA 80,458,1952
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
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REVIEWS:
ORGANIZATION
|
STANDARD
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REFERENCE
TOXICOLOGY REVIEW
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HUTOX* -,419,1996
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
|
N/R
|
N/R
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
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REFERENCE
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: A1287; | Number of Industries 1; Total Number of Facilities 33; Number of Occupations 1; Total Number of Employees Exposed 297
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: A1287 |
Number of Industries 1; Total Number of Facilities 25; Number of Occupations 2; Total Number of Employees Exposed 591; Total Number of Female Employees Exposed 492 | ||||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
N/R
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REFERENCES:
CODEN
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REFERENCE
HUTOX*
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PSEBAA
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Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1903/04-
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