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Propionic acid, ethyl ester

RTECS #: UF3675000

CAS #: 105-37-3

UPDATE: October 1997 MW: 102.15 MF: C5H10O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Ethyl propanoate
  2. Ethylester kyseliny propionove (Czech)
  3. Propanoic acid, ethyl ester
  1. Propionate d'ethyle (French)
  2. Propionic ether


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		100 mg moderate ATDAEI 1,161,1992
skin
rabbit 		500 mg/24 hour moderate FCTXAV 16,749,1978


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 1,158 mg/kg N/R AGGHAR 18,109,1960
intraperitoneal
rat 		lethal dose (50 percent kill): 1,200 mg/kg N/R FCTXAV 16,749,1978
oral
rat 		lethal dose (50 percent kill): 8,732 mg/kg Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Other changes

Gastrointestinal: Other changes 		ATDAEI 1,174,1992
skin
rabbit 		lowest published lethal dose: 14,256 mg/kg Lung, Thorax, or Respiration: Other changes ATDAEI 1,174,1992


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80173;
Number of Industries 2;
Total Number of Facilities 63;
Number of Occupations 19;
Total Number of Employees Exposed 3,459
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80173;
Number of Industries 4;
Total Number of Facilities 1,132;
Number of Occupations 11;
Total Number of Employees Exposed 8,988;
Total Number of Female Employees Exposed 3,615


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
AGGHAR Archiv fuer Gewerbepathologie und Gewerbehygiene. (Berlin, Ger.) V.1-18, 1930-61. For publisher information, see IAEHDW.
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990-
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7.

RTECS Compound Description:
   Primary Irritant

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