RTECS:TY4900000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

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1,2 - Propanediol, diacetate

RTECS #: TY4900000

CAS #: 623-84-7

UPDATE: August 2006 MW: 160.19 MF: C₇H₁₂O₄

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

SKIN AND EYE IRRITATION DATA:

ACUTE TOXICITY DATA:

STANDARDS AND REGULATIONS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

Propylene glycol diacetate

alpha - Propylene glycol diacetate

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
eye
rabbit 500 mg moderate AJOPAA 29,1363,1946
skin
human 107 mg/3 day- intermittent mild 85DKA8 -,127,1977

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
guinea pig lethal dose (50 percent kill): 3,420 mg/kg Behavioral: General anesthetic

Gastrointestinal: Other changes

Kidney, Ureter, and Bladder: Other changes JIHTAB 23,259,1941
oral
rat lethal dose (50 percent kill): 13,530 mg/kg N/R JIHTAB 23,259,1941

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - DENMARK time-weighted average 100 ppm (tentative), OCT 2002

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: M2739;
Number of Industries 1;
Total Number of Facilities 112;
Number of Occupations 4;
Total Number of Employees Exposed 2,016

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY

REFERENCES:
CODEN
REFERENCE

85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918-
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU.

RTECS Compound Description:
Human Data
Primary Irritant

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