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| UPDATE: October 1995 | MW: N/R | MF: N/R |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
|
N/R
|
N/R
|
| |||
REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
implant | rat
lowest published toxic dose: 293 mg/kg
|
Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Liver: Tumors Blood: Lymphoma including Hodgkin's disease
JNCIAM 33,1005,1964
|
implant | rat
toxic dose : 10 gm/kg
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Immunological Including Allergic: Increase in cellular immune response
BJSUAM 52,49,1965
|
intratracheal | rat
lowest published toxic dose: 225 mg/kg
|
Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Lung, Thorax, or Respiration: Emphysema Lung, Thorax, or Respiration: Fibrosis (interstitial)
EVHPAZ 11,109,1975
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
inhalation | human
lowest published toxic concentration: 12 mg/m3/11 week- continuous
|
Eye: Visual field changes
|
IAEHDW 57,297,1986
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
International Agency for Research on Cancer (IARC) Cancer Review
|
Human No Adequate Data
|
IMEMDT 19,303,1979
|
International Agency for Research on Cancer (IARC) Cancer Review
|
Animal Inadequate Evidence
|
IMEMDT 19,303,1979
|
International Agency for Research on Cancer (IARC) Cancer Review
|
Group 3
|
IMSUDL 7,56,1987
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TOXICOLOGY REVIEW
|
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AOHYA3 17,143,1974
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STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
| ||
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
National Occupational Exposure Survey 1983
|
National Occupational Exposure Survey 1983: Hazard Code: X3289 |
 ;Number of Industries 9; Total Number of Facilities 924; Number of Occupations 17; Total Number of Employees Exposed 22,176; Total Number of Female Employees Exposed 15,667 | |||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
|
REFERENCE
N/R
|
| ||
REFERENCES:
CODEN
|
|
REFERENCE
AOHYA3
|
Annals of Occupational Hygiene. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford,
NY 10523) V.1- 1958-
|
BJSUAM
|
British Journal of Surgery. (Quadrant Subscription Services Ltd., Oakfield House, Perrymount
Rd., Haywards Heath, W. Sussex RH16 3DH, UK) V.1- 1913-
|
EVHPAZ
|
EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents,
Washington, DC 20402) No.1- 1972-
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IAEHDW
|
International Archives of Occupational and Environmental Health. (Springer-Verlag New York,
Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.35- 1975-
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IMEMDT
|
IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications
Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
|
IMSUDL
|
IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY
12210) No.1- 1979-
|
JNCIAM
|
Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher
information, see JJIND8.
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