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| UPDATE: December 1999 | MW: 268.44 | MF: C18H24N2 |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
oral | rat
lethal dose (50 percent kill): 3,580 mg/kg
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Eye: Other eye effects | Behavioral: Food intake (animal) Gastrointestinal: Hypermotility, diarrhea
ATDAEI 1,67,1990
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skin | rabbit
lethal dose (50 percent kill): >7,940 mg/kg
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Behavioral: Food intake (animal) | Behavioral: Change in motor activity (specific assay)
ATDAEI 1,67,1990
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
oral | rat
lowest published toxic dose: 5,607 mg/kg/90 day- continuous
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Liver: Changes in liver weight | Blood: Normocytic anemia Blood: Changes in leukocyte (WBC) count
NTIS** OTS0545431
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
|
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REFERENCE
N/R
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N/R
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N/R
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: T1079 |
Number of Industries 6; Total Number of Facilities 717; Number of Occupations 25; Total Number of Employees Exposed 20,590; Total Number of Female Employees Exposed 1,118 | |||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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Used as antioxidant/antiozonant/antifatigue agent for natural and synthetic rubber
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EPA TSCA Section 8(d) unpublished health/safety studies
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EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8854;8EHQ-0892-9282
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EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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REFERENCES:
CODEN
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REFERENCE
ATDAEI
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Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert,
Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990-
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NTIS**
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National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information.
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