RTECS:SS9040000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

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p - Phenylenediamine, N,N' - di - sec - butyl -

RTECS #: SS9040000

CAS #: 101-96-2

UPDATE: December 1999 MW: 220.40 MF: C₁₄H₂₄N₂

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

SKIN AND EYE IRRITATION DATA:

ACUTE TOXICITY DATA:

OTHER MULTIPLE DOSE DATA:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

1,4 - Benzenediamine, N,N' - bis (1 - methylpropyl) - (9CI)

Antioxidant 22

CP 40182

Kerobit BPD

N,N' - Di - sek.butyl - p - fenylendiamin (Czech)

N,N' - Di - s - butyl - p - phenylenediamine

Santoflex 44

Tenamene 2

Topanol M

UOP 5

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
eye
rabbit 100 無/24 hour severe NTIS OTS0555010
skin
rabbit 500 無/24 hour severe NTIS OTS0555010

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
inhalation
rat lowest published lethal concentration: 600 mg/m³/6 hour N/R KODAK* 21MAY1971
intraperitoneal
mammal (species unspecified) lethal dose (50 percent kill): 10 mL/kg N/R IPSTB3 3,93,1976
oral
rat lethal dose (50 percent kill): 148 mg/kg Behavioral: Somnolence (general depressed activity)

Gastrointestinal: Other changes

Kidney, Ureter, and Bladder: Other changes in urine composition NTIS OTS0555010
skin
guinea pig lethal dose (50 percent kill): 5 gm/kg N/R RCTEA4 45,627,1972
skin
rabbit lethal dose (50 percent kill): 2,806 mg/kg Behavioral: Tremor

Kidney, Ureter, and Bladder: Other changes in urine composition

Skin: After systemic exposure: Dermatitis, other NTIS OTS0555010

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
rat lowest published toxic dose: 2,800 mg/kg/28 day- continuous Behavioral: Food intake (animal)

Liver: Liver function tests impaired

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field NTIS OTS0545434

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X6950;
Number of Industries 3;
Total Number of Facilities 184;
Number of Occupations 11;
Total Number of Employees Exposed 9,196;
Total Number of Female Employees Exposed 257

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as an antioxidant
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

REFERENCES:
CODEN
REFERENCE**

IPSTB3 International Polymer Science and Technology. (Rapra Technology Ltd., Shawbury, Shrewsbury, Shropshire SY4 4NR, UK)
KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650)
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
RCTEA4 Rubber Chemistry and Technology. (American Chemical Soc., Rubber Division, c/o Mrs. M.E. Bauer, Univ. of Akron, Akron, OH 44325) V.1- 1928-

Used as an antioxidant

RTECS Compound Description:
Primary Irritant

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