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p - Phenylenediamine, 2 - chloro - , sulfate

RTECS #: SS9000000

CAS #: 6219-71-2

UPDATE: April 1999 MW: 827.14 MF: C6H5ClN2•xH2O4S


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. TUMORIGENIC DATA:
  3. NIOSH DOCUMENTATION AND SURVEILLANCE:
  4. STATUS IN FEDERAL AGENCIES:
  5. REFERENCES:

SYNONYMS:

  1. 2 - Chloro - 1,4 - benzenediamine sulfate
  2. 2 - Chloro - p - phenylenediamine sulfate
  3. 2 - Cl - p - PD
  4. 3 - Chloro - 4 - aminoaniline sulfate
  5. C.I. 76066
  1. C.I. Oxidation Base 13A
  2. Fourrine 81
  3. Fourrine SO
  4. NCI - C03316
  5. Renal SO


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lowest published toxic dose: 194 gm/kg/77 week- continuous Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Liver: Tumors 		CRNGDP 1,495,1980
oral
mouse 		toxic dose : 12,150 gm/kg/96 week- continuous Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Liver: Tumors 		CRNGDP 1,495,1980
oral
rat 		lowest published toxic dose: 41 gm/kg/77 week- continuous Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Kidney, Ureter, and Bladder: Kidney tumors

Liver: Tumors 		CRNGDP 1,495,1980


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X2756;
Number of Industries 1;
Total Number of Facilities 626;
Number of Occupations 1;
Total Number of Employees Exposed 5,537;
Total Number of Female Employees Exposed 2,853


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as colorants in hair dyes
NCI Carcinogenesis Bioassay (feed);inadequate studies:mouse,rat NCITR* NCI-TR-113,1978


REFERENCES:

CODEN
REFERENCE
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*.

Used as colorants in hair dyes

RTECS Compound Description:
   Tumorigen

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