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Phenanthridinium, 3,8 - diamino - 5 - methyl - 6 - phenyl - , bromide

RTECS #: SF7960500

CAS #: 518-67-2

UPDATE: December 1995 MW: 380.32 MF: C20H18N3•Br


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. REFERENCES:

SYNONYMS:

  1. 2,7 - Diamino - 10 - methyl - 9 - phenylphenanthridinium bromide
  2. 3,8 - Diamino - 5 - methyl - 6 - phenylphenanthridinium bromide
  3. 6C46
  4. Dimidium bromide
  1. Phenanthridinium 1553
  2. Phenanthridinium compound 1553
  3. Trypadine


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intravenous
mouse 		lethal dose (50 percent kill): 7,300 µg/kg N/R BJPCAL 5,261,1950
subcutaneous
mouse 		lethal dose (50 percent kill): 61 mg/kg N/R BJPCAL 1,65,1946


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intramuscular
guinea pig 		lowest published toxic dose: 10 mg/kg/5 day- intermittent Liver: Fatty liver degeneration BJPCAL 1,65,1946


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X6236;
Number of Industries 1;
Total Number of Facilities 34;
Number of Occupations 2;
Total Number of Employees Exposed 67;
Total Number of Female Employees Exposed 34


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
N/R


REFERENCES:

CODEN
REFERENCE
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM.

RTECS Compound Description:
   Drug

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