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Phenanthrenequinone

RTECS #: SF7875000

CAS #: 84-11-7

UPDATE: August 2006 MW: 208.22 MF: C₁₄H₈O₂

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

MUTATION DATA:

TUMORIGENIC DATA:

ACUTE TOXICITY DATA:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

9,10 - Phenanthraquinone

9,10 - Phenanthrenedione

9,10 - Phenanthrenequinone

Phenanthrene, 9,10 - dihydro - 9,10 - dioxo -

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
DNA repair Bacillus subtilis 400 痢/plate MUREAV 66,337,1979
mutation in microorganisms Salmonella typhimurium 30 痠ol/L (-enzymatic activation step) PNASA6 81,1696,1984

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
skin
mouse lowest published toxic dose: 800 mg/kg/29 week- continuous Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Skin and Appendages: Tumors

Tumorigenic: Tumors at site of application PIATA8 16,309,1940

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
intraperitoneal
mouse lowest published lethal dose: 165 mg/kg N/R HBTXAC 5,110,1959
intratracheal
mouse lowest published toxic dose: 32.3 痢/kg Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation JAPTO* 25,47,2005

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X5889;
Number of Industries 4;
Total Number of Facilities 306;
Number of Occupations 4;
Total Number of Employees Exposed 3,675;
Total Number of Female Employees Exposed 632

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

REFERENCES:
CODEN
REFERENCE

HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59
JAPTO* Journal of Applied Toxicology (John Wiley & Sons, Ltd., Oldlands Way Bognor Regis West Sussex, PO22 9SA England) V.1- 1981-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
PIATA8 Proceedings of the Imperial Academy of Tokyo. (Tokyo, Japan) V.1-21, 1912-45. For publisher information, see PJACAW.
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915-

RTECS Compound Description:
   Agricultural Chemical
   Tumorigen
   Mutagen

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