RTECS:RZ2464000 The Registry of Toxic Effects of Chemical Substances

1,3 - Pentadiene

RTECS #: RZ2464000

CAS #: 504-60-9

UPDATE: February 2006 MW: 68.13 MF: C₅H₈

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

ACUTE TOXICITY DATA:

STANDARDS AND REGULATIONS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

1 - Methylbutadiene

Piperylene

RCRA waste number U186

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
inhalation
human lowest published toxic concentration: 850 mg/m³/5 minute Behavioral: Somnolence (general depressed activity) VCVGH* -,69,1990
inhalation
mouse lethal concentration (50 percent kill): 1,100 mg/m³/2 hour N/R 85GMAT -,101,1982
inhalation
mouse lethal concentration (50 percent kill): 9,760 mg/m³/2 hour Behavioral: Somnolence (general depressed activity)

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea VCVGH* -,68,1990
inhalation
mouse lethal concentration (16 percent kill): 8,650 mg/m³/2 hour Behavioral: Somnolence (general depressed activity)

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea VCVGH* -,68,1990
inhalation
mouse lethal concentration (84 percent kill): 14,300 mg/m³/2 hour Behavioral: Somnolence (general depressed activity)

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea VCVGH* -,68,1990
inhalation
rat lethal concentration (50 percent kill): 140 gm/m³/2 hour N/R 85GMAT -,101,1982
inhalation
rat lethal concentration (50 percent kill): 97,200 mg/m³/4 hour Behavioral: Somnolence (general depressed activity)

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea VCVGH* -,68,1990
inhalation
rat lethal concentration (16 percent kill): 70,000 mg/m³/4 hour Behavioral: Somnolence (general depressed activity)

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea VCVGH* -,68,1990
inhalation
rat lethal concentration (84 percent kill): 280,000 mg/m³/4 hour Behavioral: Somnolence (general depressed activity)

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea VCVGH* -,68,1990

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - RUSSIA short term exposure limit 40 mg/m³, JUN2003

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 82971;
Number of Industries 1;
Total Number of Facilities 20;
Number of Occupations 2;
Total Number of Employees Exposed 614
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 82971;
Number of Industries 1;
Total Number of Facilities 3;
Number of Occupations 3;
Total Number of Employees Exposed 68

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in fillers, packifiers, linear aliphatic resins
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9276
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

REFERENCES:
CODEN
REFERENCE

85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

Used in fillers, packifiers, linear aliphatic resins

RTECS Compound Description:
Human Data

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SYNONYMS:
1 - Methylbutadiene Piperylene	RCRA waste number U186

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST	ROUTE/ ORGANISM/ TISSUE	DOSE	REFERENCE
N/R	N/R	N/R	N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
inhalation human	lowest published toxic concentration: 850 mg/m³/5 minute	Behavioral: Somnolence (general depressed activity)	VCVGH* -,69,1990
inhalation mouse	lethal concentration (50 percent kill): 1,100 mg/m³/2 hour	N/R	85GMAT -,101,1982
inhalation mouse	lethal concentration (50 percent kill): 9,760 mg/m³/2 hour	Behavioral: Somnolence (general depressed activity) Behavioral: Ataxia Lung, Thorax, or Respiration: Dyspnea	VCVGH* -,68,1990
inhalation mouse	lethal concentration (16 percent kill): 8,650 mg/m³/2 hour	Behavioral: Somnolence (general depressed activity) Behavioral: Ataxia Lung, Thorax, or Respiration: Dyspnea	VCVGH* -,68,1990
inhalation mouse	lethal concentration (84 percent kill): 14,300 mg/m³/2 hour	Behavioral: Somnolence (general depressed activity) Behavioral: Ataxia Lung, Thorax, or Respiration: Dyspnea	VCVGH* -,68,1990
inhalation rat	lethal concentration (50 percent kill): 140 gm/m³/2 hour	N/R	85GMAT -,101,1982
inhalation rat	lethal concentration (50 percent kill): 97,200 mg/m³/4 hour	Behavioral: Somnolence (general depressed activity) Behavioral: Ataxia Lung, Thorax, or Respiration: Dyspnea	VCVGH* -,68,1990
inhalation rat	lethal concentration (16 percent kill): 70,000 mg/m³/4 hour	Behavioral: Somnolence (general depressed activity) Behavioral: Ataxia Lung, Thorax, or Respiration: Dyspnea	VCVGH* -,68,1990
inhalation rat	lethal concentration (84 percent kill): 280,000 mg/m³/4 hour	Behavioral: Somnolence (general depressed activity) Behavioral: Ataxia Lung, Thorax, or Respiration: Dyspnea	VCVGH* -,68,1990

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

STANDARDS AND REGULATIONS:
ORGANIZATION	STANDARD	REFERENCE
Occupational Exposure Limit - RUSSIA	short term exposure limit 40 mg/m³, JUN2003

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION	STANDARD or SURVEY	REFERENCE
National Occupational Hazard Survey 1974	National Occupational Hazard Survey 1974: Hazard Code: 82971; Number of Industries 1; Total Number of Facilities 20; Number of Occupations 2; Total Number of Employees Exposed 614
National Occupational Exposure Survey 1983	National Occupational Exposure Survey 1983: Hazard Code: 82971; Number of Industries 1; Total Number of Facilities 3; Number of Occupations 3; Total Number of Employees Exposed 68

STATUS IN FEDERAL AGENCIES:
ORGANIZATION	REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in fillers, packifiers, linear aliphatic resins
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9276
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

REFERENCES:
CODEN	REFERENCE
85GMAT	"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
VCVGH*	"Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.