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| UPDATE: January 1997 | MW: N/R | MF: N/R |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
skin | guinea pig
100 mg/24 hour
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moderate
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CTOIDG 94(8),41,1979
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skin | human
300 mg/3 day- intermittent
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mild
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85DKA8 -,127,1977
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skin | rat
100 mg/24 hour
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mild
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CTOIDG 94(8),41,1979
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skin | rabbit
100 mg/24 hour
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moderate
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CTOIDG 94(8),41,1979
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
mutation in microorganisms
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Salmonella typhimurium
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10 µL/plate (-enzymatic activation step)
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FCTXAV 18,467,1980
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
oral | mouse
lowest published toxic dose: 952 gm/kg/1 year- intermittent
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Gastrointestinal: Tumors
IJMRAQ 61,422,1973
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oral | mouse
toxic dose : 1,040 gm/kg/1 year- intermittent
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Gastrointestinal: Tumors
IJCNAW 10,652,1972
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subcutaneous | mouse
lowest published toxic dose: 160 gm/kg/17 week- intermittent
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Tumorigenic: Tumors at site of application
IJCNAW 10,652,1972
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subcutaneous | mouse
toxic dose : 360 gm/kg/39 week- intermittent
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Skin and Appendages: Tumors
IJCNAW 10,652,1972
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subcutaneous | mouse
toxic dose : 329 gm/kg/39 week- intermittent
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Tumorigenic: Tumors at site of application
IJMRAQ 61,422,1973
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skin | mouse
lowest published toxic dose: 1,757 gm/kg/88 week- intermittent
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Skin and Appendages: Tumors
IJMRAQ 61,422,1973
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skin | mouse
toxic dose : 2,276 gm/kg/81 week- continuous
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Skin and Appendages: Tumors
IJCNAW 10,652,1972
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
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N/R
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REVIEWS:
ORGANIZATION
|
STANDARD
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REFERENCE
N/R
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N/R
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N/R
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
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REFERENCE
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: A1216; | Number of Industries 6; Total Number of Facilities 480; Number of Occupations 13; Total Number of Employees Exposed 14,484
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: A1216 |
Number of Industries 11; Total Number of Facilities 1,896; Number of Occupations 20; Total Number of Employees Exposed 21,393; Total Number of Female Employees Exposed 7,447 | ||||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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REFERENCES:
CODEN
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REFERENCE
85DKA8
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"Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V.A., and P. Lazar,
eds., New York, Academic Press, Inc. 1977
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CTOIDG
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Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976-
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FCTXAV
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Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see
FCTOD7.
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IJCNAW
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International Journal of Cancer. (International Union Against Cancer, 3 rue du Conseil-
General, 1205 Geneva, Switzerland) V.1- 1966-
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IJMRAQ
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Indian Journal of Medical Research. (Indian Council of Medical Research, Ansari Nagar, New
Delhi 110 029, India) V.1- 1913-
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