UPDATE: August 2008

MW: N/R

MF: N/R

NOTE:

• TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.
  

TABLE OF CONTENTS:

1. ACUTE TOXICITY DATA:
   
2. OTHER MULTIPLE DOSE DATA:
   
3. STANDARDS AND REGULATIONS:
   
4. NIOSH DOCUMENTATION AND SURVEILLANCE:
   
5. STATUS IN FEDERAL AGENCIES:
   
6. REFERENCES:
   

SYNONYMS:
N/R	N/R

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST	ROUTE/ ORGANISM/ TISSUE	DOSE	REFERENCE
N/R	N/R	N/R	N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
intradermal guinea pig	lowest published toxic dose: 400 µg/kg	Immunological Including Allergic: Hypersensitivity delayed (multiple organ involvement)	TOVEFN (5),54,2002
inhalation mammal (species unspecified)	lowest published toxic concentration: 91 mg/m3	Lung, Thorax, or Respiration: Other changes	TOVEFN (5),54,2002
intraperitoneal mouse	lethal dose (50 percent kill): 2,100 mg/kg	Eye: Ptosis Behavioral: Somnolence (general depressed activity) Behavioral: Convulsions or effect on seizure threshold	YACHDS 3,2427,1975
intraperitoneal rat	lethal dose (50 percent kill): 2,550 mg/kg	N/R	YACHDS 3,2427,1975
oral mouse	lethal dose (50 percent kill): >10,000 mg/kg	N/R	TOVEFN (5),54,2002
oral rat	lethal dose (50 percent kill): >10,000 mg/kg	N/R	TOVEFN (5),54,2002
subcutaneous mouse	lethal dose (50 percent kill): 3,870 mg/kg	Skin and Appendages: Other: Hair	YACHDS 3,2427,1975
subcutaneous rat	lethal dose (50 percent kill): >5 gm/kg	N/R	YACHDS 3,2427,1975

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
inhalation guinea pig	lowest published toxic concentration: 5 mg/m3/14 day- intermittent	Immunological Including Allergic: Hypersensitivity delayed (multiple organ involvement)	TOVEFN (5),54,2002

REVIEWS:
ORGANIZATION	STANDARD	REFERENCE
N/R	N/R	N/R

STANDARDS AND REGULATIONS:
ORGANIZATION	STANDARD	REFERENCE
Occupational Exposure Limit - RUSSIA	short term exposure limit 1 mg/m3, MAR2004

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION	STANDARD or SURVEY	REFERENCE
National Occupational Hazard Survey 1974	National Occupational Hazard Survey 1974: Hazard Code: A1238; Number of Industries 7; Total Number of Facilities 382; Number of Occupations 8; Total Number of Employees Exposed 2,817
National Occupational Exposure Survey 1983	National Occupational Exposure Survey 1983: Hazard Code: A1238; Number of Industries 2; Total Number of Facilities 220; Number of Occupations 14; Total Number of Employees Exposed 5,421; Total Number of Female Employees Exposed 4,011
National Occupational Exposure Survey 1983	National Occupational Exposure Survey 1983: Hazard Code: X9696; Number of Industries 1; Total Number of Facilities 16; Number of Occupations 1; Total Number of Employees Exposed 94; Total Number of Female Employees Exposed 62

STATUS IN FEDERAL AGENCIES:
ORGANIZATION	REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY

REFERENCES:
CODEN	REFERENCE
TOVEFN	Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown
YACHDS	Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972-

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