RTECS:RH3420000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

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7 - Octen - 2 - ol, 2,6 - dimethyl -

RTECS #: RH3420000

CAS #: 18479-58-8

UPDATE: February 2009 MW: 156.30 MF: C₁₀H₂₀O

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

SKIN AND EYE IRRITATION DATA:

REPRODUCTIVE EFFECTS DATA:

ACUTE TOXICITY DATA:

OTHER MULTIPLE DOSE DATA:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

2,6 - Dimethyl - 7 - octen - 2 - ol

Dihydromyrcenol

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
skin
rabbit 500 mg/24 hour mild FCTXAV 12,525,1974

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
rat lowest published toxic dose: 11 gm/kg (7-17 day pregnant) Reproductive: Other effects to embryo or fetus

Reproductive: Specific developmental abnormalities: Musculoskeletal system TOXID9 -,313,2008

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
rat lethal dose (50 percent kill): 3,600 mg/kg N/R FCTXAV 12,525,1974
skin
rabbit lethal dose (50 percent kill): >5 gm/kg N/R FCTXAV 12,525,1974

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
rat lowest published toxic dose: 4,550 mg/kg/13 week- intermittent Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in both tubules and glomeruli

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) TOXID9 -,104,2008
oral
rat lowest published toxic dose: 45,500 mg/kg/13 week- intermittent Liver: Multiple effects

Kidney, Ureter, and Bladder: Changes in kidney weight

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) TOXID9 -,104,2008
oral
rat lowest published toxic dose: 91,000 mg/kg/13 week- intermittent Liver: Multiple effects

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain TOXID9 -,104,2008
oral
rat lowest published toxic dose: 11,000 mg/kg/11 day- intermittent Behavioral: Food intake (animal)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain TOXID9 -,313,2008

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X2821;
Number of Industries 46;
Total Number of Facilities 4,330;
Number of Occupations 46;
Total Number of Employees Exposed 58,447;
Total Number of Female Employees Exposed 16,516

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY

REFERENCES:
CODEN
REFERENCE

FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7.
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-

Used as fragrance raw material

RTECS Compound Description:
Reproductive Effector
Primary Irritant

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