UPDATE: January 1997

MW: 250.59

MF: Cl3Nd

NOTE:

• TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.
  

TABLE OF CONTENTS:

1. SKIN AND EYE IRRITATION DATA:
   
2. ACUTE TOXICITY DATA:
   
3. REVIEWS:
   
4. NIOSH DOCUMENTATION AND SURVEILLANCE:
   
5. STATUS IN FEDERAL AGENCIES:
   
6. REFERENCES:
   

SYNONYMS:
N/R	N/R

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
eye rabbit	50 mg	N/R	TXAPA9 6,614,1964
skin rabbit	500 mg/24 hour	mild	TXAPA9 6,614,1964

MUTATION DATA AND REFERENCES:
SYSTEM TEST	ROUTE/ ORGANISM/ TISSUE	DOSE	REFERENCE
N/R	N/R	N/R	N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
intraperitoneal guinea pig	lethal dose (50 percent kill): 140 mg/kg	Behavioral: Somnolence (general depressed activity) Behavioral: Food intake (animal)	AMIHAB 15,9,1957
intraperitoneal mouse	lethal dose (50 percent kill): 347 mg/kg	Behavioral: Somnolence (general depressed activity) Behavioral: Food intake (animal) Lung, Thorax, or Respiration: Other changes	AEHLAU 5,437,1962
intraperitoneal rat	lethal dose (50 percent kill): 150 mg/kg	N/R	EQSSDX 1,1,1975
intravenous guinea pig	lethal dose (50 percent kill): 122 mg/kg	N/R	EQSSDX 1,1,1975
intravenous rat	lethal dose (50 percent kill): 3,500 µg/kg	N/R	AMIHAB 16,475,1957
intravenous rabbit	lethal dose (50 percent kill): 139 mg/kg	N/R	EQSSDX 1,1,1975
oral mouse	lethal dose (50 percent kill): 3,692 mg/kg	N/R	EQSSDX 1,1,1975
subcutaneous frog	lethal dose (50 percent kill): 434 mg/kg	N/R	EQSSDX 1,1,1975
subcutaneous guinea pig	lethal dose (50 percent kill): 243 mg/kg	N/R	EQSSDX 1,1,1975
subcutaneous mouse	lethal dose (50 percent kill): 278 mg/kg	N/R	EQSSDX 1,1,1975
subcutaneous rat	lowest published lethal dose: 150 mg/kg	N/R	AIPTAK 37,305,1930
unreported route mammal (species unspecified)	lowest published lethal dose: 40 mg/kg	N/R	AIPTAK 37,305,1930

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

REVIEWS:
ORGANIZATION	STANDARD	REFERENCE
TOXICOLOGY REVIEW		JPMSAE 54,663,1965

STANDARDS AND REGULATIONS:
ORGANIZATION	STANDARD	REFERENCE
N/R	N/R	N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION	STANDARD or SURVEY	REFERENCE
National Occupational Exposure Survey 1983	National Occupational Exposure Survey 1983: Hazard Code: X3718; Number of Industries 1; Total Number of Facilities 31; Number of Occupations 1; Total Number of Employees Exposed 627; Total Number of Female Employees Exposed 31

STATUS IN FEDERAL AGENCIES:
ORGANIZATION	REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY

REFERENCES:
CODEN	REFERENCE
AEHLAU	Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960-
AIPTAK	Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898-
AMIHAB	AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU.
EQSSDX	Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued.
JPMSAE	Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961-
TXAPA9	Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

RTECS Compound Description:
   Primary Irritant

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