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Naphtha (petroleum) , light catalytic cracked

RTECS #: QK8000000

CAS #: 64741-55-5

UPDATE: July 2000 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. REPRODUCTIVE EFFECTS DATA:
  4. ACUTE TOXICITY DATA:
  5. OTHER MULTIPLE DOSE DATA:
  6. REVIEWS:
  7. STANDARDS AND REGULATIONS:
  8. NIOSH DOCUMENTATION AND SURVEILLANCE:
  9. STATUS IN FEDERAL AGENCIES:
  10. REFERENCES:

SYNONYMS:

  1. Light catalytically cracked naphtha


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
rabbit 		500 mg mild ATDAEI 1,119,1990


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 7,500 ppm/6 hour (14 day prior to copulation/0-19 day pregnant) Reproductive: Other effects on female JTEHF8 58,365,1999


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration : >19,800 mg/m3/6 hour Olfaction: Other olfaction effects

Behavioral: Change in motor activity (specific assay)

Behavioral: Ataxia 		NTIS** OTS0535706
oral
rat 		lethal dose : >5 gm/kg Gastrointestinal: Hypermotility, diarrhea ATDAEI 1,119,1990
skin
rabbit 		lowest published lethal dose: 3 gm/kg N/R ATDAEI 1,119,1990


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 7,500 ppm/13 week- intermittent Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in kidney weight 		TOXID9 48,325,1999
oral
rat 		lowest published toxic dose: 10 gm/kg/4 week- intermittent Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) TIHEEC 1(3),67,1985
skin
rat 		lowest published toxic dose: 56 gm/kg/28 day- intermittent Blood: Changes in bone marrow not included in above

Skin: After systemic exposure: Dermatitis, irritative 		JTEHF8 58,365,1999


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
International Agency for Research on Cancer (IARC) Cancer Review Animal Limited Evidence IMEMDT 45,39,1989


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 500 ppm (2000 mg/m3), JAN1993
Occupational Exposure Limit - TURKEY time-weighted average 500 ppm (2000 mg/m3), JAN1993


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: Y1033;
Number of Industries 4;
Total Number of Facilities 267;
Number of Occupations 7;
Total Number of Employees Exposed 8,904;
Total Number of Female Employees Exposed 239


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990-
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
JTEHF8 Journal of Toxicology and Environmental Health, Part A. (Taylor & Francis, 47 Runway Rd., Suite G, Levittown, PA 19057) V.53- 1998-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
TIHEEC Toxicology and Industrial Health. (Princeton Scientific Pub. Co., POB 2155, Princeton, NJ 08540) V.1- 1985-
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-

RTECS Compound Description:
   Tumorigen
   Reproductive Effector
   Primary Irritant

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