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| UPDATE: February 2007 | MW: 712.70 | MF: C32H22N6O7S2•2Na |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
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intraperitoneal | rat
lethal dose (50 percent kill): 560 mg/kg
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Behavioral: Somnolence (general depressed activity) | Kidney, Ureter, and Bladder: Other changes in urine composition Skin: After systemic exposure: Dermatitis, other
TOVEFN (2),34,1998
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intraperitoneal | rat
lethal dose (50 percent kill): 560 mg/kg
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Behavioral: Somnolence (general depressed activity)
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TOVEFN (2),40,1998
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ocular | rabbit
lowest published toxic dose: 25 mg/kg
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Eye: Conjunctiva irritation
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TOVEFN (2),40,1998
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oral | mouse
lethal dose (50 percent kill): 7,900 mg/kg
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Behavioral: Somnolence (general depressed activity) | Kidney, Ureter, and Bladder: Other changes in urine composition Skin: After systemic exposure: Dermatitis, other
TOVEFN (2),34,1998
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oral | mouse
lethal dose (50 percent kill): 7,900 mg/kg
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Behavioral: Somnolence (general depressed activity)
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TOVEFN (2),40,1998
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oral | rat
lethal dose (50 percent kill): >10 gm/kg
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Behavioral: Somnolence (general depressed activity) | Kidney, Ureter, and Bladder: Other changes in urine composition Skin: After systemic exposure: Dermatitis, other
TOVEFN (2),34,1998
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oral | rat
lethal dose (50 percent kill): >10,000 mg/kg
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Behavioral: Somnolence (general depressed activity)
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TOVEFN (2),40,1998
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
oral | rat
lowest published toxic dose: 30 gm/kg/30 day- intermittent
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Brain and Coverings: Recordings from specific areas of CNS | Liver: Liver function tests impaired Blood: Pigmented or nucleated red blood cells
TOVEFN (2),34,1998
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oral | rat
lowest published toxic dose: 30,000 mg/kg/30 day- intermittent
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Vascular: Other changes | Liver: Liver function tests impaired Liver: Other changes
TOVEFN (2),40,1998
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oral | rat
lowest published toxic dose: 30,000 mg/kg/30 day- intermittent
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Liver: Changes in liver weight | Kidney, Ureter, and Bladder: Other changes Kidney, Ureter, and Bladder: Changes in kidney weight
TOVEFN (2),40,1998
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oral | rat
lowest published toxic dose: 30,000 mg/kg/30 day- intermittent
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Endocrine: Changes in spleen weight | Blood: Normocytic anemia Blood: Other changes
TOVEFN (2),40,1998
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
N/R
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N/R
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N/R
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STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
N/R
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REFERENCES:
CODEN
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REFERENCE
TOVEFN
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Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown
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