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1 - Naphthaleneacetic acid

RTECS #: QJ0875000

CAS #: 86-87-3

UPDATE: August 2003 MW: 186.22 MF: C12H10O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. ACUTE TOXICITY DATA:
  5. OTHER MULTIPLE DOSE DATA:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. 1 - NAA
  2. 1 - Naphthylacetic acid
  3. 2 - (1 - Naphthyl) acetic acid
  4. ANU
  5. Acide naphthylacetique (French)
  6. Agronaa
  7. Alman
  8. Alphaspra
  9. Appl - set
  10. Biokor
  11. Celmone
  12. Fruitofix
  13. Fruitone N
  14. Klingtite
  15. Kyselina 1 - naftyloctova (Czech)
  16. Liqui - stik
  17. NAA
  18. NAA 800
  19. NU - Tone
  20. Nafusaku
  21. Naphthaleneacetic acid
  22. Naphthalene - 1 - acetic acid
  23. Naphthylacetic acid
  24. Naphyl - 1 - essigsaeure (German)
  1. Niagara - stik
  2. Phyomone
  3. Pimacol - sol
  4. Planofix
  5. Planofixe
  6. Plucker
  7. Pomoxon
  8. Primacol
  9. Rasin
  10. Rhodofix
  11. STIK
  12. Stafast
  13. Stop - Drop
  14. Tekkam
  15. Tip - Off
  16. Transplantone
  17. Tre - Hold
  18. Vardhak
  19. alpha - Naa
  20. alpha - Naphthaleneacetic acid
  21. alpha - Naphthylacetic
  22. alpha - Naphthylacetic acid
  23. alpha - Naphthyleneacetic acid
  24. alpha - Naphthylessigsaeure (German)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		100 mg severe PESTC* 9,10,1980


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
cytogenetic analysis hamster lung 10 mmol/L/6 hour (+/-enzymatic activation step) MUREAV 517,187,2002
mutation in microorganisms Saccharomyes cerevisiae 500 mg/L (-enzymatic activation step) IDZAAW 48,185,1973
other mutation test systems human leukocyte 100 nmol/L EXPEAM 32,29,1976


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): >207 gm/m3 N/R PESTC* 9,10,1980
intraperitoneal
mouse 		lethal dose (50 percent kill): 609 mg/kg N/R TOIZAG 15,443,1968
intraperitoneal
rat 		lethal dose (50 percent kill): 100 mg/kg N/R PESTC* 9,10,1980
oral
mouse 		lethal dose (50 percent kill): 743 mg/kg N/R TOIZAG 14,132,1967
oral
rat 		lethal dose (50 percent kill): 1 gm/kg N/R 85DPAN -,-,1971/1976
subcutaneous
mouse 		lethal dose (50 percent kill): 733 mg/kg N/R TOIZAG 15,443,1968
skin
rabbit 		lethal dose (50 percent kill): >5 gm/kg N/R PEMNDP 9,607,1991


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 27 gm/kg/90 day- continuous Behavioral: Food intake (animal)

Liver: Changes in liver weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		TXCYAC 5,371,1976
oral
rat 		lowest published toxic dose: 30 gm/kg/30 day- intermittent Liver: Changes in liver weight

Blood: Pigmented or nucleated red blood cells

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		GISAAA 55(4),93,1990


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Supported RBREV* -,137,1998


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80317;
Number of Industries 1;
Total Number of Facilities 43;
Number of Occupations 8;
Total Number of Employees Exposed 605
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80317;
Number of Industries 1;
Total Number of Facilities 287;
Number of Occupations 1;
Total Number of Employees Exposed 3,732;
Total Number of Female Employees Exposed 574


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used to induce flowering, prevent preharvest fruit drop, stimulate and accelerate rooting
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
IDZAAW Japanese Journal of Genetics. Idengaku Zasshi. (Genetics Soc. of Japan, 111 Tanida, Mishima, Shizuoka-ken, Japan) V.1- 1921-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968-
PESTC* Pesticide & Toxic Chemical News. (Food Chemical News, Inc., 400 Wyatt Bldg., 777 14th St., NW, Washington, DC 20005) V.1- 1972-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954-
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973-

Used to induce flowering, prevent preharvest fruit drop, stimulate and accelerate rooting

RTECS Compound Description:
   Agricultural Chemical
   Mutagen
   Human Data
   Primary Irritant

ALT CAS #: 61913-11-9
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