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Methanaminium, N,N,N - trimethyl - , hydroxide

RTECS #: PA0875000

CAS #: 75-59-2

UPDATE: December 1999 MW: 91.18 MF: C4H12N•HO


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Ammonium, tetramethyl - , hydroxide
  2. Hydroxyde de tetramethylammonium (French)
  3. Megaposit CD 14
  4. NMD 3
  1. NMW - W
  2. OCG 945
  3. TMAH
  4. Tetramethylammonium hydroxide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intravenous
rabbit 		lowest published lethal dose: 1 mg/kg N/R 85IXA4 -,688,1948
parenteral
frog 		lowest published lethal dose: 5 mg/kg Vascular: BP elevation not characterized in autonomic section 85IXA4 -,688,1948
subcutaneous
mouse 		lowest published lethal dose: 19 mg/kg N/R JPETAB 28,367,1926
skin
guinea pig 		lethal dose (50 percent kill): 25 mg/kg Skin: After systemic exposure: Dermatitis, other NTIS** OTS0570994
unreported route
frog 		lowest published lethal dose: 1,515 µg/kg N/R 85IXA4 -,681,1948


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
rat 		lowest published toxic dose: 1 gm/kg/4 week- intermittent Behavioral: Change in motor activity (specific assay)

Lung, Thorax, or Respiration: Pulmonary emboli

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		NTIS** OTS0559697


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: A1009;
Number of Industries 1;
Total Number of Facilities 48;
Number of Occupations 1;
Total Number of Employees Exposed 48
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: A1009;
Number of Industries 6;
Total Number of Facilities 105;
Number of Occupations 16;
Total Number of Employees Exposed 6,413;
Total Number of Female Employees Exposed 1,446


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in semiconductor photolithography processes
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

Used in semiconductor photolithography processes

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