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Methane, diiodo -

RTECS #: PA8575000

CAS #: 75-11-6

UPDATE: June 2000 MW: 267.83 MF: CH2I2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Diiodomethane
  2. Dijodmethan (Czech)
  3. MI - Gee
  1. Methylene diiodide
  2. Methylene iodide
  3. Methylenjodid (Czech)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
mutation in microorganisms Escherichia coli 3 mg/plate (-enzymatic activation step) MUREAV 416,169,1998


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 467 mg/kg N/R 34ZIAG -,756,1969
intraperitoneal
rat 		lethal dose (50 percent kill): 403 mg/kg N/R 34ZIAG -,756,1969
oral
child 		lowest published lethal dose: 2,778 µL/kg Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Acute pulmonary edema 		AEMED3 19,1171,1990
subcutaneous
mouse 		lethal dose (50 percent kill): 830 mg/kg N/R TXAPA9 4,354,1962


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: A1158;
Number of Industries 1;
Total Number of Facilities 31;
Number of Occupations 1;
Total Number of Employees Exposed 311
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: A1158;
Number of Industries 1;
Total Number of Facilities 7;
Number of Occupations 2;
Total Number of Employees Exposed 42


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969
AEMED3 Annals of Emergency Medicine. (American College of Emergency Physicians, 1125 Executive Circle, Irving, TX 75038)
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

RTECS Compound Description:
   Mutagen
   Human Data

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