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Methacrylic acid, dodecyl ester

RTECS #: OZ4300000

CAS #: 142-90-5

UPDATE: November 2007 MW: 254.46 MF: C16H30O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Acrylic acid, 2 - methyl - , dodecyl ester
  2. Ageflex FM 246
  3. Dodecyl methacrylate
  4. Dodecyl 2 - methyl - 2 - propenoate
  1. Lauryl methacrylate
  2. Laurylester kyseliny methakrylove (Czech)
  3. Methacrylic acid, lauryl ester


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		500 mg/24 hour mild 85JCAE -,373,1986
skin
rabbit 		500 mg/24 hour mild 85JCAE -,373,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 25 gm/kg N/R JPMSAE 62,778,1973
intraperitoneal
rat 		lethal dose (50 percent kill): 12 gm/kg N/R AMPMAR 36,58,1975
intravenous
dog 		lowest published lethal dose: 1,240 µL/kg N/R JPMSAE 63,376,1974


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
EVHPAZ 11,141,1975
TOXICOLOGY REVIEW
IJTOFN 24,53,2005


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: A1466;
Number of Industries 31;
Total Number of Facilities 1,524;
Number of Occupations 22;
Total Number of Employees Exposed 10,594
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: A1466;
Number of Industries 12;
Total Number of Facilities 405;
Number of Occupations 11;
Total Number of Employees Exposed 7,247;
Total Number of Female Employees Exposed 574


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE FEREAC 47,26992,82
Used for copolymerization in casting, adhesives and coatings
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
AMPMAR Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. (SPPIF, B.P.22, F-41353 Vineuil, France) V.7- 1946-
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
IJTOFN International Journal of Toxicology. (Taylor & Francis, 47 Runway Rd., Suite g, Levittown, PA 19057) V.16- 1997-
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961-

Used for copolymerization in casting, adhesives and coatings

RTECS Compound Description:
   Primary Irritant

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