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Mercury sulfide

RTECS #: OX0720000

CAS #: 1344-48-5

UPDATE: May 2009 MW: 232.65 MF: HgS


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. OTHER MULTIPLE DOSE DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Almaden
  2. C.I. 77766
  3. C.I. Pigment Red 106
  4. Chinese vermilion
  5. Cinnabar
  6. Ethiops mineral
  7. Mercuric Sulfide Red
  8. Mercuric Sulfide, Black
  9. Mercuric sulfide
  10. Mercury monosulfide
  1. Mercury sulphide
  2. Mercury (2+) sulfide
  3. Monomercury sulfide
  4. Orange vermilion
  5. Pigment Red 106
  6. Red cinnabar
  7. Red mercury sulphide
  8. Scarlet vermilion
  9. Vermilion
  10. beta - Mercuric sulfide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
guinea pig 		lowest published toxic dose: 14,000 mg/kg/7 day- intermittent Ear: Changes in vestibular functions

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases

Biochemical: Metabolism (intermediary): Effect on Na-K pump 		AEPPAE 364,249,2001
oral
guinea pig 		lowest published toxic dose: 700 mg/kg/7 day- intermittent Ear: Changes in vestibular functions AEPPAE 364,249,2001
oral
guinea pig 		lowest published toxic dose: 7,000 mg/kg/7 day- intermittent Ear: Change in cochlear structure or function

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases

Biochemical: Metabolism (intermediary): Effect on Na-K pump 		AEPPAE 364,249,2001
oral
mouse 		lowest published toxic dose: 195 mg/kg/4 week- intermittent Endocrine: Evidence of thyroid hypofunction BECTA6 49,847,1992
oral
mouse 		lowest published toxic dose: 70 mg/kg/1 week- intermittent Behavioral: Somnolence (general depressed activity)

Behavioral: Change in motor activity (specific assay) 		TXAPA9 224,192,2007
oral
mouse 		lowest published toxic dose: 210 mg/kg/3 week- intermittent Behavioral: Somnolence (general depressed activity)

Behavioral: Change in motor activity (specific assay) 		TXAPA9 224,192,2007
oral
mouse 		lowest published toxic dose: 420 mg/kg/6 week- intermittent Brain and Coverings: Other degenerative changes

Behavioral: Altered sleep time (including change in righting reflex)

Behavioral: Ataxia 		TXAPA9 224,192,2007
oral
mouse 		lowest published toxic dose: 420 mg/kg/6 week- intermittent Brain and Coverings: Other degenerative changes

Behavioral: Altered sleep time (including change in righting reflex) 		TXAPA9 224,192,2007
oral
mouse 		lowest published toxic dose: 490 mg/kg/7 week- intermittent Behavioral: Ataxia TXAPA9 224,192,2007
oral
mouse 		lowest published toxic dose: 770 mg/kg/11 week- intermittent Liver: Other changes

Kidney, Ureter, and Bladder: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases 		TXAPA9 224,192,2007
oral
mouse 		lowest published toxic dose: 490 mg/kg/7 week- intermittent Blood: Other changes

Biochemical: Metabolism (intermediary): Other 		TXAPA9 224,192,2007
oral
mouse 		lowest published toxic dose: 350 mg/kg/5 week- intermittent Blood: Other changes

Biochemical: Metabolism (intermediary): Other 		TXAPA9 224,192,2007
oral
rat 		lowest published toxic dose: 14,000 mg/kg/14 day- intermittent Behavioral: Change in psychophysiological tests

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases 		TOLED5 169,109,2007
oral
rat 		lowest published toxic dose: 25 gm/kg/5 day- intermittent Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) TXAPA9 227,417,2008


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.025 mg(Hg)/m3 (skin) DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not classifiable as human carcinogen DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
HUTOX* -,515,1996


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.003 ppm (0.025 mg(Hg)/m3), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 0.025 mg(Hg)/m3, Skin, MAR2002
Occupational Exposure Limit - HUNGARY time-weighted average 0.08 mg(Hg)/m3, short term exposure limit 0.32 mg(Hg)/m3, Skin, SEP2000
Occupational Exposure Limit - KOREA time-weighted average 0.1 mg(Hg)/m3, skin, 2006
Occupational Exposure Limit - NEW ZEALAND time-weighted average 0.025 mg(Hg)/m3, JAN2002
Occupational Exposure Limit - RUSSIA time-weighted average 0.05 mg(Hg)/m3, short term exposure limit 0.2 mg(Hg)/m3, Skin, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 0.03 mg(Hg)/m3, Skin, JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 0.1 mg(Hg)/m3,KZG- week 0.8 mg(Hg)/m3, DEC2006


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: M1643;
Number of Industries 2;
Total Number of Facilities 13;
Number of Occupations 3;
Total Number of Employees Exposed 98


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC.
BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
HUTOX*
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

Used in Chinese medicine

RTECS Compound Description:
   Natural Product

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