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| UPDATE: May 2009 | MW: 454.39 | MF: HgI2 |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
inhalation | rat
lowest published toxic concentration: 4,870 ng/m3/24 hour (1-22 day pregnant)
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Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants) | Reproductive: Effects on embryo or fetus: Fetal death
GISAAA 46(5),73,1981
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inhalation | rat
lowest published toxic concentration: 450 ng/m3/24 hour (1-22 day pregnant)
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Reproductive: Effects on embryo or fetus: Extra embryonic structures (e.g., placenta, umbilical cord) | Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)
GISAAA 46(5),73,1981
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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intraperitoneal | mouse
lethal dose (50 percent kill): 4,200 µg/kg
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N/R
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GTPZAB 25(7),27,1981
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oral | man
lowest published lethal dose: 357 mg/kg
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Lung, Thorax, or Respiration: Dyspnea | Gastrointestinal: Hypermotility, diarrhea Gastrointestinal: Nausea or vomiting
ZKMEAB 106,783,1927
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oral | mouse
lethal dose (50 percent kill): 17 mg/kg
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N/R
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GTPZAB 25(7),27,1981
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oral | rat
lethal dose (50 percent kill): 18 mg/kg
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N/R
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TOVEFN (4),27,1994
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skin | rat
lethal dose (50 percent kill): 75 mg/kg
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N/R
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GTPZAB 25(7),27,1981
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
inhalation | rat
lowest published toxic concentration: 25 µg/m3/17 week- intermittent
|
Blood: Eosinophilia | Blood: Other changes Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases
GISAAA 51(4),29,1986
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intraperitoneal | rat
lowest published toxic dose: 5,950 µg/kg/17 week- intermittent
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Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases
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GTPZAB 28(5),46,1984
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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time-weighted average 0.025 mg(Hg)/m3 (skin)
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DTLVS* TLV/BEI,2007
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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Not classifiable as human carcinogen
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DTLVS* TLV/BEI,2007
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TOXICOLOGY REVIEW
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HUTOX* -,515,1996
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
|
|
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air
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time-weighted average 0.05 mg(Hg)/m3
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DTLWS* 3,22,1973
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Occupational Exposure Limit - AUSTRALIA
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time-weighted average 0.003 ppm (0.025 mg(Hg)/m3), JUL2008
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Occupational Exposure Limit - BELGIUM
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time-weighted average 0.025 mg(Hg)/m3, Skin, MAR2002
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Occupational Exposure Limit - FINLAND
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time-weighted average 0.05 mg(Hg)/m3, JAN1999
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Occupational Exposure Limit - FRANCE
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VME 0.1 mg(Hg)/m3, Skin, FEB2006
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Occupational Exposure Limit - HUNGARY
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time-weighted average 0.08 mg(Hg)/m3, short term exposure limit 0.32 mg(Hg)/m3, Skin, SEP2000
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Occupational Exposure Limit - KOREA
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time-weighted average 0.1 mg(Hg)/m3, skin, 2006
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Occupational Exposure Limit - NEW ZEALAND
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time-weighted average 0.025 mg(Hg)/m3, JAN2002
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Occupational Exposure Limit - NORWAY
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time-weighted average 0.05 mg(Hg)/m3, JAN1999
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Occupational Exposure Limit - THE PHILIPPINES
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time-weighted average 0.05 mg(Hg)/m3, JAN1993
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Occupational Exposure Limit - POLAND
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MAC(time-weighted average) 0.05 mg(Hg)/m3, MAC(short term exposure limit) 0.15 mg(Hg)/m3, JAN1999
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Occupational Exposure Limit - RUSSIA
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time-weighted average 0.05 mg(Hg)/m3, short term exposure limit 0.2 mg(Hg)/m3, Skin, JUN2003
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Occupational Exposure Limit - SWEDEN
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time-weighted average 0.03 mg(Hg)/m3, Skin, JUN2005
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Occupational Exposure Limit - SWITZERLAND
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MAK- week 0.1 mg(Hg)/m3,KZG- week 0.8 mg(Hg)/m3, DEC2006
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Occupational Exposure Limit - THAILAND
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short term exposure limit 0.05 mg(Hg)/m3, JAN1993
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Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value; | Not classifiable as human carcinogen
Occupational Exposure Limit IN SINGAPORE, VIETNAM
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value |
Not classifiable as human carcinogen | ||||||||||||||||||
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
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REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO MERCURY, ARYL AND INORGANIC-air
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ceiling concentration 0.1 mg/m3 (Sk)
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NIOSH* DHHS #92-100,1992
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National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: 81888; | Number of Industries 6; Total Number of Facilities 385; Number of Occupations 7; Total Number of Employees Exposed 2,333
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: 81888 |
Number of Industries 8; Total Number of Facilities 272; Number of Occupations 10; Total Number of Employees Exposed 3,504; Total Number of Female Employees Exposed 1,902 | ||||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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REFERENCES:
CODEN
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REFERENCE
DTLVS*
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The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by
American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
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DTLWS*
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"Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For
publisher information, see 85INA8.
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GISAAA
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Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga,
113095 Moscow, USSR) V.1- 1936-
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GTPZAB
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Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see
MTPEEI
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HUTOX*
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NIOSH*
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National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and
Welfare, Reports and Memoranda.
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TOVEFN
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Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown
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ZKMEAB
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Zeitschrift fuer Klinische Medizin. (Berlin, Fed. Rep. Ger.) V.1-158, 1879-1965. For
publisher information, see EJCIB8.
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