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Mercury, (3 - ( ( (3 - carboxy - 2,2,3 - trimethylcyclopentyl) carbonyl) amino) - 2 - methoxypropyl) (mercaptoacetato - S) - , disodium salt

RTECS #: OV8700000

CAS #: 21259-76-7

UPDATE: May 2009 MW: 608.07 MF: C16H27HgNO6S•2Na


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. STANDARDS AND REGULATIONS:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. REFERENCES:

SYNONYMS:

  1. Disodium N - (3 - (carboxymethylthiomercuri) - 2 - methoxypropyl) - alpha - camphoramate
  2. Diucardyn sodium
  3. Mercaptomerin sodium
  1. N - (gamma - Carboxymethylmercaptomercuri - beta - methoxy) propylcamphoramic acid disodium salt
  2. Sodium mercaptomerin
  3. Thiomerin sodium


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intramuscular
rat 		lethal dose (50 percent kill): 15 mg/kg N/R FEPRA7 8,316,1949
intravenous
rat 		lowest published lethal dose: 250 mg/kg N/R JPETAB 99,149,1950
intravenous
rabbit 		lowest published lethal dose: 125 mg/kg N/R JPETAB 99,149,1950
subcutaneous
rat 		lowest published lethal dose: 14 mg/kg N/R CLDND*


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.05 mg(Hg)/m3 DTLWS* 3,22,1973
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.01 mg(Hg)/m3, short term exposure limit 0.03 mg(Hg)/m3, JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 0.01 mg(Hg)/m3, short term exposure limit 0.03 mg(Hg)/m3, Skin, MAR2002
Occupational Exposure Limit - FINLAND time-weighted average 1 mg(Hg)/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 0.1 mg(Hg)/m3, Skin, FEB2006
Occupational Exposure Limit - HUNGARY time-weighted average 0.01 mg(Hg)/m3, short term exposure limit 0.04 mg(Hg)/m3, Skin, SEP2000
Occupational Exposure Limit - NORWAY time-weighted average 0.05 mg(Hg)/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.05 mg(Hg)/m3, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.05 mg(Hg)/m3, MAC(short term exposure limit) 0.15 mg(Hg)/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 0.05 mg(Hg)/m3, short term exposure limit 0.2 mg(Hg)/m3, Skin, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 0.01 mg(Hg)/m3, Skin, JUN2005
Occupational Exposure Limit - THAILAND short term exposure limit 0.05 mg(Hg)/m3, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO MERCURY, ORGANO-air time-weighted average 0.01 mg/m3;
short term exposure limit 0.03 mg/m3 (Sk) 		NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X5296;
Number of Industries 1;
Total Number of Facilities 7;
Number of Occupations 2;
Total Number of Employees Exposed 628;
Total Number of Female Employees Exposed 314


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
N/R


REFERENCES:

CODEN
REFERENCE
DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8.
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87.
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.

FDA-proprietary drug

RTECS Compound Description:
   Drug
   Organometallic

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