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| UPDATE: April 1995 | MW: 985.25 | MF: C49H76O20 |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
|
N/R
|
N/R
|
| |||
REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
intraduodenal | guinea pig
lethal dose (50 percent kill): >10 mg/kg
|
Cardiac: Cardiomyopathy including infarction | Cardiac: Arrythmias (indlucing changes in conduction)
ARZNAD 21,225,1971
|
intraperitoneal | mouse
lethal dose (50 percent kill): 7 mg/kg
|
N/R
|
AIPTAK 155,165,1965
|
intraperitoneal | pigeon
lethal dose (50 percent kill): 220 µg/kg
|
N/R
|
JPPMAB 14,96,1962
|
intraperitoneal | rat
lowest published lethal dose: 10 mg/kg
|
N/R
|
TXAPA9 1,156,1959
|
intravenous | cat
lowest published lethal dose: 230 µg/kg
|
N/R
|
ARZNAD 19,657,1969
|
intravenous | dog
lethal dose (50 percent kill): 340 µg/kg
|
Cardiac: Other changes
|
IVEJAC 57,31,1980
|
intravenous | frog
lethal dose (50 percent kill): 790 µg/kg
|
N/R
|
NYKZAU 61,231,1965
|
intravenous | guinea pig
lowest published lethal dose: 502 µg/kg
|
N/R
|
ARZNAD 17,1237,1967
|
intravenous | mouse
lethal dose (50 percent kill): 8,100 µg/kg
|
N/R
|
NIIRDN 6,877,1982
|
intravenous | pigeon
lowest published lethal dose: 300 µg/kg
|
N/R
|
JPPMAB 14,96,1962
|
intravenous | rat
lethal dose (50 percent kill): 16,500 µg/kg
|
Behavioral: Convulsions or effect on seizure threshold
|
ARZNAD 11,848,1961
|
oral | guinea pig
lethal dose (50 percent kill): 100 mg/kg
|
N/R
|
ARZNAD 15,481,1965
|
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
TOXICOLOGY REVIEW
|
|
85ELDJ -,192,1963
|
| ||
STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
| ||
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
National Occupational Exposure Survey 1983
|
National Occupational Exposure Survey 1983: Hazard Code: X7405 |
 ;Number of Industries 2; Total Number of Facilities 17; Number of Occupations 7; Total Number of Employees Exposed 9,179; Total Number of Female Employees Exposed 7,452 | |||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
|
REFERENCE
N/R
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REFERENCES:
CODEN
|
|
REFERENCE
85ELDJ
|
"Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB
Georg Thieme, 1963
|
AIPTAK
|
Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of
Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898-
|
ARZNAD
|
Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960
Aulendorf, Fed. Rep. Ger.) V.1- 1951-
|
IVEJAC
|
Indian Veterinary Journal. (Dr. R. Krishnamurti, G.M.V.C., 8 Avenue Rd., Madras 600 034,
India) V.1- 1924-
|
JPPMAB
|
Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High
St., London SEI 7JN, UK) V.1- 1949-
|
NIIRDN
|
Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan)
|
NYKZAU
|
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto
Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-
1944-
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TXAPA9
|
Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1959-
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