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Lactic acid, ethyl ester

RTECS #: OD5075000

CAS #: 97-64-3

UPDATE: May 2008 MW: 118.15 MF: C5H10O3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. STANDARDS AND REGULATIONS:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Actylol
  2. Acytol
  3. Ethyl 2 - hydroxypropionate
  4. Ethyl alpha - hydroxypropionate
  1. Ethyl lactate
  2. Ethylester kyseliny mlecne (Czech)
  3. Lactate d'ethyle (French)
  4. Solactol


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intramuscular
guinea pig 		lowest published lethal dose: 2,605 mg/kg Lung, Thorax, or Respiration: Dyspnea JPETAB 76,189,1942
intraperitoneal
rat 		lowest published lethal dose: 1 gm/kg Behavioral: Muscle weakness

Lung, Thorax, or Respiration: Cyanosis

Lung, Thorax, or Respiration: Other changes 		JPPMAB 11,150,1959
intravenous
mouse 		lethal dose (50 percent kill): 600 mg/kg N/R JPETAB 65,89,1939
oral
mouse 		lethal dose (50 percent kill): 2,500 mg/kg N/R JPETAB 65,89,1939
oral
rat 		lethal dose (50 percent kill): >2,000 mg/kg N/R FEREAC 67,56225,2002
subcutaneous
mouse 		lethal dose (50 percent kill): 2,500 mg/kg N/R JPETAB 65,89,1939
skin
rat 		lethal dose (50 percent kill): >5,000 mg/kg N/R FEREAC 69,34945,2004
skin
rabbit 		lethal dose (50 percent kill): >5 gm/kg N/R FCTOD7 20,677,1982
unreported route
rat 		lethal dose (50 percent kill): 5,000 mg/kg N/R HBPTO* 1,825,2001


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - DENMARK time-weighted average 10 ppm (tentative), OCT 2002
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 20 mg/m3, 2003
Occupational Exposure Limit - SWEDEN time-weighted average 5 ppm (25 mg/m3);
short term exposure limit 10 ppm (50 mg/m3), JUN2005


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: A1136;
Number of Industries 2;
Total Number of Facilities 41;
Number of Occupations 8;
Total Number of Employees Exposed 578
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: A1136;
Number of Industries 5;
Total Number of Facilities 298;
Number of Occupations 23;
Total Number of Employees Exposed 7,298;
Total Number of Female Employees Exposed 1,962


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
HBPTO* Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949-

Used as solvent for NITROCELLULOSE, CELLULOSE ACETATE, many CELLULOSE ETHERS, resins, paints

RTECS Compound Description:
   Agricultural Chemical

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