|
|
|
|
|
|
|
|
|
|
| UPDATE: November 2007 | MW: 197.89 | MF: IO3•Na |
SYNONYMS:
|
|
| |
SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
|
N/R
|
N/R
|
| |||
REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
intraperitoneal | mouse
lethal dose (50 percent kill): 119 mg/kg
|
Behavioral: Convulsions or effect on seizure threshold | Behavioral: Excitement Lung, Thorax, or Respiration: Other changes
JPETAB 120,171,1957
|
intravenous | dog
lowest published lethal dose: 200 mg/kg
|
N/R
|
HBTXAC 1,274,1955
|
intravenous | dog
lowest published toxic dose: 30 mg/kg
|
Eye: Retinal changes pigmentary deposition, retinitis, other)
|
TOLED5 166,115,2006
|
intravenous | mouse
lethal dose (50 percent kill): 108 mg/kg
|
Behavioral: Convulsions or effect on seizure threshold | Behavioral: Excitement Lung, Thorax, or Respiration: Other changes
JPETAB 120,171,1957
|
intravenous | rabbit
lowest published lethal dose: 75 mg/kg
|
Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change | Behavioral: Convulsions or effect on seizure threshold Kidney, Ureter, and Bladder: Proteinuria
JPETAB 40,451,1930
|
oral | mouse
lethal dose (50 percent kill): 505 mg/kg
|
Behavioral: Food intake (animal)
|
JPETAB 120,171,1957
|
| |||
OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
TOXICOLOGY REVIEW
|
|
JACTDZ 14,231,1995
|
| ||
STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
| ||
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
National Occupational Hazard Survey 1974
|
National Occupational Hazard Survey 1974: Hazard Code: 84430; | Number of Industries 1; Total Number of Facilities 222; Number of Occupations 3; Total Number of Employees Exposed 1,620
National Occupational Exposure Survey 1983
|
National Occupational Exposure Survey 1983: Hazard Code: 84430 |
 ;Number of Industries 4; Total Number of Facilities 582; Number of Occupations 8; Total Number of Employees Exposed 8,972; Total Number of Female Employees Exposed 6,739 | ||||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
|
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
|
| ||
REFERENCES:
CODEN
|
|
REFERENCE
HBTXAC
|
"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59
|
JACTDZ
|
Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New
York, NY 10128) V.1-12, 1982-1993. Discontinued.
|
JPETAB
|
Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E.
Preston St., Baltimore, MD 21202) V.1- 1909/10-
|
TOLED5
|
Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands)
V.1- 1977-
|
| |
