RTECS:NH3486800 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

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Hypochlorous acid, sodium salt, pentahydrate

RTECS #: NH3486800

CAS #: 10022-70-5

UPDATE: August 2007 MW: 164.54 MF: ClO•Na•5H₂O

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

MUTATION DATA:

OTHER MULTIPLE DOSE DATA:

REVIEWS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

REFERENCES:

SYNONYMS:

Bleach

Caustic soda bleach

Dakin's solution

Household laundry bleach

Sodium hypochlorite pentahydrate

Surgical chlorinated soda solution

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
DNA damage human leukocyte 0.5 ppm/1 hour MUTAEX 19,157,2004
DNA damage multiple
other fish 0.1 ppm/72 hour- continuous MUREAV 587,103,2005
mutation in microorganisms Saccharomyes cerevisiae 10 ppm/2 hour MUTAEX 19,157,2004
micronucleus test multiple
other fish 0.5 ppm/72 hour- continuous MUREAV 587,103,2005

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
multiple
non-mammalian species lowest published toxic dose: 0.2 ppm/72 hour- continuous Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field MUREAV 587,103,2005
oral
rat lowest published toxic dose: 8.75 gm/kg/14 day- continuous Nutritional and Gross Metabolic: Dehydration VCVN5* -,380,1989

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

International Agency for Research on Cancer (IARC) Cancer Review Animal Inadequate Evidence IMEMDT 52,159,1991
International Agency for Research on Cancer (IARC) Cancer Review Human No Available Data IMEMDT 52,159,1991
International Agency for Research on Cancer (IARC) Cancer Review Group 3 IMEMDT 52,159,1991
TOXICOLOGY REVIEW
ENTOX* -,317,2005

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X7253;
Number of Industries 1;
Total Number of Facilities 4;
Number of Occupations 3;
Total Number of Employees Exposed 979;
Total Number of Female Employees Exposed 33

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

N/R

REFERENCES:
CODEN
REFERENCE

ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986-
VCVN5* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.

RTECS Compound Description:
   Tumorigen
   Mutagen
   Primary Irritant

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