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Hydroquinone, trimethyl -

RTECS #: MX7820000

CAS #: 700-13-0

UPDATE: September 1999 MW: 152.21 MF: C9H12O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. REPRODUCTIVE EFFECTS DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. 1,4 - Benzenediol, 2,3,5 - trimethyl - (9CI)
  2. 1,4 - Dihydroxy - 2,3,5 - trimethylbenzene
  3. 2,3,5 - Trimethyl - 1,4 - benzenediol
  4. 2,3,5 - Trimethylhydroquinone
  5. 3,6 - Dihydroxypseudocumol
  1. Pseudocumohydroquinone
  2. TMHQ
  3. Trimethylhydroquinone
  4. psi - Cumohydroquinone


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
subcutaneous
rat 		lowest published toxic dose: 20 mg/kg (4 day prior to copulation) Reproductive: Maternal effects: Ovaries, fallopian tubes

Reproductive: Maternal effects: Uterus, cervix, vagina 		JSICAZ 19,264,1960


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): 1,500 mg/m3/4 hour Eye: Corneal damage

Cardiac: Other changes

Lung, Thorax, or Respiration: Emphysema 		BGTOX* 5,125,1993
intraperitoneal
mouse 		lethal dose (50 percent kill): 65 mg/kg Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Dyspnea 		BGTOX* 5,125,1993
oral
rat 		lethal dose (50 percent kill): 3,200 mg/kg Lung, Thorax, or Respiration: Other changes BGTOX* 5,125,1993
skin
rabbit 		lethal dose (50 percent kill): >200 mg/kg N/R BGTOX* 5,125,1993


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83814;
Number of Industries 1;
Total Number of Facilities 21;
Number of Occupations 3;
Total Number of Employees Exposed 705
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83814;
Number of Industries 1;
Total Number of Facilities 4;
Number of Occupations 1;
Total Number of Employees Exposed 114


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as an intermediate
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
BGTOX* BG Chemie: Toxicological Evaluations, Five Potential Health Hazards of Existing Chemicals. (Springer-Verlag New York, POB 2485, Secaucus, NJ 07096).
JSICAZ Journal of Scientific and Industrial Research, Section C: Biological Sciences. (New Delhi, India) V.14-21, 1955-62. For publisher information, see IJEBA6.

Used as an intermediate

RTECS Compound Description:
   Reproductive Effector

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