RTECS:LZ5250000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

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Gluconic acid, compd. with quinidine (1:1) , D -

RTECS #: LZ5250000

CAS #: 7054-25-3

UPDATE: August 2007 MW: 520.64 MF: C₂₀H₂₄N₂O₂•C₆H₁₂O₇

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

ACUTE TOXICITY DATA:

REVIEWS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

REFERENCES:

SYNONYMS:

Cinchonan - 9 - ol, 6' - methoxy - , (9S) - , mono - D - gluconate (salt)

Quinaglute

Quinidine gluconate

Quinidine, D - gluconate (salt)

Quinidine mono - D - gluconate (salt)

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
intraperitoneal
mouse lowest published lethal dose: 150 mg/kg N/R TXAPA9 23,288,1972
intravenous
human lowest published toxic dose: 4 mg/kg Cardiac: Arrythmias (indlucing changes in conduction)

Endocrine: Differential effect of sex or castration on observed toxicity CLPTAT 67,413,2000
oral
man lowest published toxic dose: 7,609 mg/kg/78 week- intermittent Skin: After systemic exposure: Dermatitis, allergic AIMDAP 145,446,1985
oral
woman lowest published toxic dose: 337 mg/kg/17 day- intermittent Blood: Changes in cell count (unspecified)

Nutritional and Gross Metabolic: Body temperature increase AJMEAZ 77,345,1984

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

TOXICOLOGY REVIEW
JEMME* 31,395,2006

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83945;
Number of Industries 1;
Total Number of Facilities 33;
Number of Occupations 1;
Total Number of Employees Exposed 66
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83945;
Number of Industries 1;
Total Number of Facilities 63;
Number of Occupations 3;
Total Number of Employees Exposed 9,094;
Total Number of Female Employees Exposed 8,028

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

N/R

REFERENCES:
CODEN
REFERENCE

AIMDAP Archives of Internal Medicine. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1908-
AJMEAZ American Journal of Medicine. (Technical Pub., 875 Third Ave., New York, NY 10022) V.1- 1946-
CLPTAT Clinical Pharmacology and Therapeutics. (American Society for Clinical Pharmacology and Therapeutics, St. Louis Mo Mosby-Year Book) V.1- 1960-
JEMME* The Journal of emergency medicine (New York : Pergamon Press) V.1- 1983-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

FDA-proprietary drug

RTECS Compound Description:
Drug
Human Data

ALT CAS #: 29826-49-1
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