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Fluorescein, 2',4',5',7' - tetrabromo -

RTECS #: LM5800000

CAS #: 15086-94-9

UPDATE: March 1999 MW: 647.92 MF: C20H8Br4O5


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. 2',4',5',7' - Tetrabromofluorescein
  2. Bromeosin
  3. C.I. 45380:2
  4. C.I. Solvent Red 43
  5. D and C Red No. 21
  6. Eosin acid
  1. Eosine acid
  2. Japan Red 223
  3. Japan Red No. 223
  4. Red No. 223
  5. Solvent Red 43
  6. Spiro (isobenzofuran - 1 (3H) ,9' - (9H) - xanthen) - 3 - one, 2',4',5',7' - tetrabromo - 3',6' - dihydroxy -


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
DNA repair Bacillus subtilis 2 mg/disc TRENAF 27,153,1976


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
subcutaneous
frog 		lowest published lethal dose: 1 gm/kg N/R HBAMAK 4,1289,1935
subcutaneous
mouse 		lowest published lethal dose: 450 mg/kg N/R HBAMAK 4,1289,1935


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
International Agency for Research on Cancer (IARC) Cancer Review Animal Inadequate Evidence IMEMDT 15,183,1977
International Agency for Research on Cancer (IARC) Cancer Review Human No Adequate Data IMEMDT 15,183,1977
International Agency for Research on Cancer (IARC) Cancer Review Group 3 IMSUDL 7,56,1987


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: T0363;
Number of Industries 2;
Total Number of Facilities 347;
Number of Occupations 5;
Total Number of Employees Exposed 7,340;
Total Number of Female Employees Exposed 1,584


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.)
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979-
TRENAF Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. (Tokyo-toritsu Eisei Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1- 1949/50-

RTECS Compound Description:
   Tumorigen
   Mutagen

ALT CAS #: 30495-79-5
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