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| UPDATE: May 2009 | MW: 134.00 | MF: C2O4•2Na |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
|
N/R
|
N/R
|
| |||
REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
intraperitoneal | mouse
lethal dose (50 percent kill): 155 mg/kg
|
N/R
|
ABMGAJ 6,498,1961
|
intraperitoneal | rat
lowest published toxic dose: 70 mg/kg
|
Kidney, Ureter, and Bladder: Renal function tests depressed | Kidney, Ureter, and Bladder: Other changes Biochemical: Metabolism (intermediary): Lipids including transport
FCTOD7 46,2274,2008
|
intravenous | human
lowest published lethal dose: 17 mg/kg
|
Behavioral: Coma | Cardiac: Arrythmias (indlucing changes in conduction) Kidney, Ureter, and Bladder: Urine volume decreased or anuria
MLDCAS 4,178,1971
|
oral | mouse
lethal dose (50 percent kill): 5,094 mg/kg
|
N/R
|
EVHPAZ 106(Suppl 2),497,1998
|
oral | rat
lethal dose (50 percent kill): 11,160 mg/kg
|
N/R
|
EVHPAZ 106(Suppl 2),497,1998
|
oral | rat
lowest published toxic dose: 536 mg/kg
|
Gastrointestinal: Hypermotility, diarrhea | Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, and Bladder: Renal function tests depressed
FCTOD7 46,1744,2008
|
subcutaneous | cat
lowest published lethal dose: 100 mg/kg
|
N/R
|
HDWU** -,-,1933
|
subcutaneous | mouse
lowest published lethal dose: 100 mg/kg
|
N/R
|
AIPTAK 8,255,1901
|
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
| |||
REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
| ||
STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
| ||
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
National Occupational Hazard Survey 1974
|
National Occupational Hazard Survey 1974: Hazard Code: 84235; | Number of Industries 14; Total Number of Facilities 940; Number of Occupations 14; Total Number of Employees Exposed 9,551
National Occupational Exposure Survey 1983
|
National Occupational Exposure Survey 1983: Hazard Code: 84235 |
 ;Number of Industries 11; Total Number of Facilities 583; Number of Occupations 12; Total Number of Employees Exposed 8,309; Total Number of Female Employees Exposed 3,508 | ||||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
|
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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REFERENCES:
CODEN
|
|
REFERENCE
ABMGAJ
|
Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher
information, see BBIADT.
|
AIPTAK
|
Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of
Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898-
|
EVHPAZ
|
EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents,
Washington, DC 20402) No.1- 1972-
|
FCTOD7
|
Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford,
NY 10523) V.20- 1982-
|
HDWU**
|
"Beitrage zur Toxikologie des Athylenoxyds und der Glykole, Dissertation," Hofbauer, A.,
Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1933
|
MLDCAS
|
Medecine Legale et Dommage Corporel. (Paris, France) V.1-7, 1968-74. Discontinued.
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