RTECS:KF5775000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

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Erythromycin, propionate (ester) , compd. with monododecyl sulfate (1:1)

RTECS #: KF5775000

CAS #: 3521-62-8

UPDATE: November 2004 MW: 1,056.56 MF: C₄₀H₇₁NO₁₄•C₁₂H₂₆O₄S

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

ACUTE TOXICITY DATA:

OTHER MULTIPLE DOSE DATA:

NIOSH DOCUMENTATION AND SURVEILLANCE:

REFERENCES:

SYNONYMS:

Eritroger

Eromycin

Erythromycin estolate

Erythromycin propionate lauryl sulfate

Erythromycin propionate, compd. with dodecyl sulfate

Erythromycin 5 - (3 - propionate) dodecyl sulfate

Erythromycin propionyl laurylsulfate

Ilosone

Lauromicina

Lauryl sulfate propionyl erythromycin ester

Neo - erycinum

Roxomicina

Stellamicina

Sulfuric acid, monododecyl ester, compd. with erythromycin propionate

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
mouse lethal dose (50 percent kill): >6,450 mg/kg N/R NIIRDN -,211,1990
oral
rat lethal dose (50 percent kill): 1,447 mg/kg N/R TXAPA9 18,185,1971
subcutaneous
mouse lethal dose (50 percent kill): >6,450 mg/kg N/R NIIRDN -,211,1990
subcutaneous
rat lethal dose (50 percent kill): >6,450 mg/kg N/R NIIRDN -,211,1990
unreported route
woman lowest published toxic dose: 100 mg/kg/5 day- intermittent Liver: Change in gall bladder structure or function CLPTAT 6,788,1965

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
rat lowest published toxic dose: 48,488 mg/kg/6 week- intermittent Skin and Appendages: Other: Hair

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field APTOA6 25,435,1967
oral
rat lowest published toxic dose: 8 gm/kg/10 day- intermittent Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) JOETD7 57,161,1997

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X5545;
Number of Industries 1;
Total Number of Facilities 39;
Number of Occupations 3;
Total Number of Employees Exposed 1,088;
Total Number of Female Employees Exposed 542

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

N/R

REFERENCES:
CODEN
REFERENCE

APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH
CLPTAT Clinical Pharmacology and Therapeutics. (American Society for Clinical Pharmacology and Therapeutics, St. Louis Mo Mosby-Year Book) V.1- 1960-
JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979-
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan)
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

FDA-proprietary drug

RTECS Compound Description:
Drug
Human Data

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