RTECS:HX7650000 The Registry of Toxic Effects of Chemical Substances

Dichromic acid, diammonium salt

RTECS #: HX7650000

CAS #: 7789-09-5

UPDATE: May 2009 MW: 252.10 MF: Cr₂H₂O₇•2H₃N

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

MUTATION DATA:

ACUTE TOXICITY DATA:

OTHER MULTIPLE DOSE DATA:

REVIEWS:

STANDARDS AND REGULATIONS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

Ammonio (bicromato di) (Italian)

Ammonio (dicromato di) (Italian)

Ammoniumbichromaat (Dutch)

Ammonium bichromate

Ammoniumdichromaat (Dutch)

Ammoniumdichromat (German)

Ammonium dichromate

Ammonium dichromate (VI)

Ammonium (dichromate d') (French)

Bichromate d'ammonium (French)

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
DNA repair Bacillus subtilis 50 mmol/L TOLED5 7,439,1981
DNA repair Salmonella typhimurium 50 mmol/L TOLED5 7,439,1981

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
child lowest published lethal dose: 99 mg/kg Gastrointestinal: Other changes

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)

Blood: Change in clotting factors AEMED3 24,748,1994
subcutaneous
guinea pig lowest published lethal dose: 25 mg/kg N/R EQSSDX 1,1,1975

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
inhalation
rat lowest published toxic concentration: 1 mg/m³/2 hour/28 week- intermittent Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Acute pulmonary edema VCVN5* -,303,1989

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

International Agency for Research on Cancer (IARC) Cancer Review Human Sufficient Evidence IMEMDT 49,49,1990
International Agency for Research on Cancer (IARC) Cancer Review Group 1 IMEMDT 49,49,1990
TOXICOLOGY REVIEW
85DHAX Cr,22,1974
TOXICOLOGY REVIEW
ENTOX* -,602,2005

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 mg(Cr)/m³ DTLVS* 3,35,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) ceiling concentration 0.1 mg(CrO3)/m³ CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) ceiling concentration 0.1 mg(CrO3)/m³ CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) ceiling concentration 0.1 mg(CrO3)/m³ CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) ceiling concentration 0.1 mg(CrO3)/m³ CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.05 mg(Cr)/m³, JUL2008
Occupational Exposure Limit - AUSTRIA TRK 0.05 mg(Cr)/m³, JAN 2006
Occupational Exposure Limit - AUSTRIA TRK 0.1 mg(Cr)/m³ (production), JAN 2006
Occupational Exposure Limit - AUSTRIA TRK 0.1 mg(Cr)/m³ (welding fumes), JAN 2006
Occupational Exposure Limit - DENMARK time-weighted average 0.005 mg(Cr)/m³, OCT 2002
Occupational Exposure Limit - FRANCE VME 0.05 mg(Cr)/m³, FEB2006
Occupational Exposure Limit - RUSSIA short term exposure limit 0.01 mg(Cr)/m³, Skin, Carcinogen, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 0.005 mg(Cr)/m³;
short term exposure limit 0.015 mg(Cr)/m³, Carcinogen, Sen, JUN2005

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CHROMIUM(VI)-air Carcinogen;
10 hour time-weighted average 0.001 mg(Cr)/m³ NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 06063;
Number of Industries 31;
Total Number of Facilities 1,812;
Number of Occupations 15;
Total Number of Employees Exposed 13,389
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 06063;
Number of Industries 23;
Total Number of Facilities 3,088;
Number of Occupations 21;
Total Number of Employees Exposed 25,163;
Total Number of Female Employees Exposed 5,017

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in lithography and photoengraving, and in manufacture of special mordants and catalysts
NTP 11th Report on Carcinogens,2004:Known to be human carcinogen

REFERENCES:
CODEN
REFERENCE

85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77
AEMED3 Annals of Emergency Medicine. (American College of Emergency Physicians, 1125 Executive Circle, Irving, TX 75038)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued.
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
VCVN5* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.

Used in lithography and photoengraving, and in manufacture of special mordants and catalysts

RTECS Compound Description:
   Tumorigen
   Mutagen
   Human Data

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SYNONYMS:
Ammonio (bicromato di) (Italian) Ammonio (dicromato di) (Italian) Ammoniumbichromaat (Dutch) Ammonium bichromate Ammoniumdichromaat (Dutch)	Ammoniumdichromat (German) Ammonium dichromate Ammonium dichromate (VI) Ammonium (dichromate d') (French) Bichromate d'ammonium (French)

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST	ROUTE/ ORGANISM/ TISSUE	DOSE	REFERENCE
DNA repair	Bacillus subtilis	50 mmol/L	TOLED5 7,439,1981
DNA repair	Salmonella typhimurium	50 mmol/L	TOLED5 7,439,1981

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
oral child	lowest published lethal dose: 99 mg/kg	Gastrointestinal: Other changes Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) Blood: Change in clotting factors	AEMED3 24,748,1994
subcutaneous guinea pig	lowest published lethal dose: 25 mg/kg	N/R	EQSSDX 1,1,1975

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
inhalation rat	lowest published toxic concentration: 1 mg/m³/2 hour/28 week- intermittent	Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi Lung, Thorax, or Respiration: Acute pulmonary edema	VCVN5* -,303,1989

REVIEWS:
ORGANIZATION	STANDARD	REFERENCE
International Agency for Research on Cancer (IARC) Cancer Review	Human Sufficient Evidence	IMEMDT 49,49,1990
International Agency for Research on Cancer (IARC) Cancer Review	Group 1	IMEMDT 49,49,1990
TOXICOLOGY REVIEW		85DHAX Cr,22,1974
TOXICOLOGY REVIEW		ENTOX* -,602,2005

STANDARDS AND REGULATIONS:
ORGANIZATION	STANDARD	REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air	time-weighted average 0.5 mg(Cr)/m³	DTLVS* 3,35,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)	ceiling concentration 0.1 mg(CrO3)/m³	CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)	ceiling concentration 0.1 mg(CrO3)/m³	CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)	ceiling concentration 0.1 mg(CrO3)/m³	CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)	ceiling concentration 0.1 mg(CrO3)/m³	CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA	time-weighted average 0.05 mg(Cr)/m³, JUL2008
Occupational Exposure Limit - AUSTRIA	TRK 0.05 mg(Cr)/m³, JAN 2006
Occupational Exposure Limit - AUSTRIA	TRK 0.1 mg(Cr)/m³ (production), JAN 2006
Occupational Exposure Limit - AUSTRIA	TRK 0.1 mg(Cr)/m³ (welding fumes), JAN 2006
Occupational Exposure Limit - DENMARK	time-weighted average 0.005 mg(Cr)/m³, OCT 2002
Occupational Exposure Limit - FRANCE	VME 0.05 mg(Cr)/m³, FEB2006
Occupational Exposure Limit - RUSSIA	short term exposure limit 0.01 mg(Cr)/m³, Skin, Carcinogen, JUN2003
Occupational Exposure Limit - SWEDEN	time-weighted average 0.005 mg(Cr)/m³; short term exposure limit 0.015 mg(Cr)/m³, Carcinogen, Sen, JUN2005

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION	STANDARD or SURVEY	REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CHROMIUM(VI)-air	Carcinogen; 10 hour time-weighted average 0.001 mg(Cr)/m³	NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974	National Occupational Hazard Survey 1974: Hazard Code: 06063; Number of Industries 31; Total Number of Facilities 1,812; Number of Occupations 15; Total Number of Employees Exposed 13,389
National Occupational Exposure Survey 1983	National Occupational Exposure Survey 1983: Hazard Code: 06063; Number of Industries 23; Total Number of Facilities 3,088; Number of Occupations 21; Total Number of Employees Exposed 25,163; Total Number of Female Employees Exposed 5,017

STATUS IN FEDERAL AGENCIES:
ORGANIZATION	REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in lithography and photoengraving, and in manufacture of special mordants and catalysts
NTP 11th Report on Carcinogens,2004:Known to be human carcinogen

REFERENCES:
CODEN	REFERENCE
85DHAX	"Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77
AEMED3	Annals of Emergency Medicine. (American College of Emergency Physicians, 1125 Executive Circle, Irving, TX 75038)
CFRGBR	Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS*	The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
ENTOX*	Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
EQSSDX	Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued.
IMEMDT	IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
NIOSH*	National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TOLED5	Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
VCVN5*	"Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.