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| UPDATE: November 2004 | MW: 480.82 | MF: C28H52N2O4 |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
|
N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
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| |||
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
inhalation | rat
lethal concentration (50 percent kill): 500 mg/m3/4 hour
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Behavioral: Tremor | Lung, Thorax, or Respiration: Dyspnea Gastrointestinal: Changes in structure or function of salivary glands
NTIS** OTS0539874
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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intraperitoneal | rat
lowest published toxic dose: 4,500 µg/kg/3 week- intermittent
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Behavioral: Somnolence (general depressed activity)
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TOSCF2 77,368,2004
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intraperitoneal | rat
lowest published toxic dose: 6,000 µg/kg/4 week- intermittent
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Behavioral: Somnolence (general depressed activity) | Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
TOSCF2 77,368,2004
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intraperitoneal | rat
lowest published toxic dose: 7,500 µg/kg/4 week- intermittent
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Behavioral: Somnolence (general depressed activity) | Cardiac: Cardiomyopathy including infarction Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
TOSCF2 77,368,2004
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oral | rat
lowest published toxic dose: 28 gm/kg/28 day- continuous
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Behavioral: Muscle weakness | Behavioral: Rigidity (includes catalepsy) Lung, Thorax, or Respiration: Other changes
NTIS** OTS0544570-1
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REVIEWS:
ORGANIZATION
|
STANDARD
|
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REFERENCE
N/R
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N/R
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N/R
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STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
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REFERENCE
N/R
|
N/R
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N/R
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
N/R
|
N/R
|
N/R
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STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
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REFERENCE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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REFERENCES:
CODEN
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REFERENCE
NTIS**
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National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information.
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TOSCF2
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Toxicological Sciences (Oxford University Press, 6277 Sea Harbor Drive, Orlando, FL 32887 )
V. 41, Jan. 1998-
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