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Coumarin, 7 - diethylamino - 4 - methyl -

RTECS #: GN6370000

CAS #: 91-44-1

UPDATE: March 1998 MW: 231.32 MF: C14H17NO2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. NIOSH DOCUMENTATION AND SURVEILLANCE:
  4. STATUS IN FEDERAL AGENCIES:
  5. REFERENCES:

SYNONYMS:

  1. 2H - 1 - Benzopyran - 2 - one, 7 - (diethylamino) - 4 - methyl - (9CI)
  2. 7 - (Diethylamino) - 4 - methyl - 2H - 1 - benzopyran - 2 - one
  3. 7 - Diethylamino - 4 - methylcoumarin
  4. 7 - Diethylamino - 4 - methylcumarin
  5. 7D4MC
  6. Aclarat 8678
  7. Blancophor AW
  8. Blancophor FFG
  9. C 47
  1. Calcofluor White RW
  2. Calcofluor White SD
  3. Coumarin 1
  4. Coumarin 47
  5. Coumarin 460
  6. Hakkol P
  7. Hiltamine Artic White SOL
  8. MDAC
  9. Uvitex WGS


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intravenous
mouse 		lethal dose (50 percent kill): 180 mg/kg N/R CSLNX* NX#03230
oral
mouse 		lethal dose (50 percent kill): 1,780 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Ataxia 		SRTCAC 36(1-4),10,1989
oral
rat 		lethal dose (50 percent kill): 5 gm/kg N/R MVCRB3 2,193,1973


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X9410;
Number of Industries 11;
Total Number of Facilities 1,470;
Number of Occupations 18;
Total Number of Employees Exposed 21,642;
Total Number of Female Employees Exposed 8,996


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as fluorescent brightener in soaps and detergents
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
MVCRB3 MVC-Report. (Stockholm, Sweden) No.1-2, 1972-73. Discontinued.
SRTCAC Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. (Tohoku University, Research Institute for Tuberculosis and Cancer, 4-1 Seiryo-machi, Sendai, Japan) V.1- 1949-

Used as fluorescent brightener in soaps and detergents

NIOSH PROFILE (FLUORESCENT WHITENING AGENTS), SRC, 12/79

RTECS Compound Description:
   Drug

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