CDC logo, Safer Healthier People CDC HomeCDC SearchCDC Health Topics A-Z
NIOSH - National Institute for Occupational Safety and Health

Search NIOSH  |  NIOSH Home  |  NIOSH Topics  |  Site Index  |  Databases and Information Resources  |  NIOSH Products  |  Contact Us




Cinnamyl alcohol

RTECS #: GE2200000

CAS #: 104-54-1

UPDATE: February 2003 MW: 134.19 MF: C9H10O


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. REPRODUCTIVE EFFECTS DATA:
  5. ACUTE TOXICITY DATA:
  6. OTHER MULTIPLE DOSE DATA:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. 2 - Propen - 1 - ol, 3 - phenyl -
  2. 3 - Fenyl - 2 - propen - 1 - ol (Czech)
  3. 3 - Phenyl - 2 - propen - 1 - ol
  4. 3 - Phenylallyl alcohol
  5. Alkohol skoricovy (Czech)
  1. Cinnamic alcohol
  2. Styrone
  3. Styryl carbinol
  4. gamma - Phenylallyl alcohol


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
rabbit 		500 mg/24 hour moderate FCTXAV 12,855,1974


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
DNA repair Bacillus subtilis 10 mg/disc OIGZDE 34,267,1985


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
unreported route
mammal (species unspecified) 		lowest published toxic dose: 535 mg/kg (4 day pregnant) Reproductive: Specific developmental abnormalities: Musculoskeletal system VCVGK* -,136,1994
unreported route
mammal (species unspecified) 		lowest published toxic dose: 535 mg/kg (10 day pregnant) Reproductive: Specific developmental abnormalities: Musculoskeletal system VCVGK* -,136,1994


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
guinea pig 		lethal dose (50 percent kill): 2,675 mg/kg N/R VCVGK* -,136,1984
oral
mouse 		lethal dose (50 percent kill): 2,675 mg/kg N/R VCVGK* -,136,1984
oral
rat 		lethal dose (50 percent kill): 2 gm/kg N/R FCTXAV 12,855,1974
skin
rabbit 		lethal dose (50 percent kill): >5 gm/kg N/R FCTXAV 12,855,1974


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 6,366 mg/kg/17 week- intermittent Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymes 		VPITAR 33(5),48,1974


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83181;
Number of Industries 6;
Total Number of Facilities 163;
Number of Occupations 36;
Total Number of Employees Exposed 8,942
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83181;
Number of Industries 25;
Total Number of Facilities 4,817;
Number of Occupations 48;
Total Number of Employees Exposed 76,974;
Total Number of Female Employees Exposed 43,896


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7.
OIGZDE Osaka-shi Igakkai Zasshi. Journal of Osaka City Medical Association. (Osaka-shi Igakkai, c/o Osaka-shiritsu Daigaku Igakubu, 1-4-54 Asahi-cho, Abeno-ku, Osaka, 545, Japan) V.24- 1975-
VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.
VPITAR Voprosy Pitaniya. Problems of Nutrition. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1932-41; V.11- 1952-

Used as flavor and fragrance component characterized by balsamic scent

RTECS Compound Description:
   Mutagen
   Reproductive Effector
   Primary Irritant

 Click Here for Additional Information about RTECS

NIOSH Home |  NIOSH Search  |  Site Index  |  Topic List |  RTECS List |  Contact Us