The Registry of Toxic Effects of Chemical Substances

C.I. Basic Brown 4

RTECS #: GC8180000

CAS #: 8005-78-5

UPDATE: November 2007 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. REVIEWS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Basic Brown 4
  2. Bismarck Brown
  3. Bismarck Brown R
  4. Bismarck Brown RLNS
  1. Bismarck Brown TSS
  2. C.I. 21010
  3. Nitrous acid, reaction products with 4 - methyl - 1,3 - benzenediamine hydrochloride


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		100 µL/24 hour severe NTIS** OTS0571845


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
mutation in microorganisms Salmonella typhimurium 10 µg/plate (-enzymatic activation step) CRNGDP 7,1921,1986


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
ENTOX* -,104,2005


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: M1443;
Number of Industries 8;
Total Number of Facilities 536;
Number of Occupations 25;
Total Number of Employees Exposed 4,312
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: M1443;
Number of Industries 3;
Total Number of Facilities 105;
Number of Occupations 7;
Total Number of Employees Exposed 2,074;
Total Number of Female Employees Exposed 293


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA GENETOX PROGRAM 1988, Negative: B subtilis rec assay


REFERENCES:

CODEN
REFERENCE
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

RTECS Compound Description:
   Mutagen
   Primary Irritant

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