RTECS:GA8746000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

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6 - Chromanol, 2,5,7,8 - tetramethyl - 2 - (4,8,12 - trimethyltridecyl) -

RTECS #: GA8746000

CAS #: 10191-41-0

UPDATE: May 2009 MW: 430.79 MF: C₂₉H₅₀O₂

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

MUTATION DATA:

OTHER MULTIPLE DOSE DATA:

REVIEWS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

(+ - ) - alpha - Tocopherol

2H - 1 - Benzopyran - 6 - ol, 3,4 - dihydro - 2,5,7,8 - tetramethyl - 2 - (4,8,12 - trimethyltridecyl) - (9CI)

Ephanyl

dl - alpha - Tocopherol

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
DNA damage intraperitoneal
rat 2,500 痢/kg CALEDQ 25,163,1984

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
oral
rat lowest published toxic dose: 800 mg/kg/8 day- intermittent Biochemical: Neurotransmitters or modulators (putative): Dopamine in striatum TXCYAC 216,140,2005

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

TOXICOLOGY REVIEW
FEREAC 73,9214,2008
TOXICOLOGY REVIEW
FEREAC 73,9214,2008
TOXICOLOGY REVIEW
MUREAV 681,93,2009

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: A1133;
Number of Industries 2;
Total Number of Facilities 104;
Number of Occupations 2;
Total Number of Employees Exposed 555
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: A1133;
Number of Industries 1;
Total Number of Facilities 4;
Number of Occupations 1;
Total Number of Employees Exposed 114

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY

REFERENCES:
CODEN
REFERENCE

CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973-

RTECS Compound Description:
Mutagen

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