RTECS:FG4725000 The Registry of Toxic Effects of Chemical Substances

Carbon tetrabromide

RTECS #: FG4725000

CAS #: 558-13-4

UPDATE: May 2009 MW: 331.65 MF: CBr₄

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

ACUTE TOXICITY DATA:

REVIEWS:

STANDARDS AND REGULATIONS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

Bromid uhlicity (Czech)

Carbon bromide

Carbon tetrabromide (ACGIH)

Methane, tetrabromide

Methane, tetrabromo -

Tetrabromomethane

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
intravenous
mouse lethal dose (50 percent kill): 56 mg/kg N/R CSLNX* NX#01612
oral
rat lethal dose : 3 gm/kg N/R VCVGH* -,583,1990
subcutaneous
mouse lethal dose (50 percent kill): 298 mg/kg N/R TXAPA9 4,354,1962

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.1 ppm;short term exposure limit 0.3 ppm DTLVS* TLV/BEI,2007

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - AUSTRALIA time-weighted average 0.1 ppm (1.4 mg/m³), short term exposure limit 0.3 ppm (4.1 mg/m³), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 0.1 ppm(1.4 mg/m³), short term exposure limit 0.3 ppm(4.2 mg/m³), MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 0.1 ppm (1.4 mg/m³), OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 0.1 ppm (1.4 mg/m³), short term exposure limit 0.4 ppm, Skin, JAN1999
Occupational Exposure Limit - FRANCE VME 0.1 ppm (1.4 mg/m³), FEB2006
Occupational Exposure Limit - KOREA time-weighted average 0.1 ppm (1.4 mg/m³), short term exposure limit 0.3 ppm (4 mg/m³), 2006
Occupational Exposure Limit - MEXICO time-weighted average 0.1 ppm (1.4 mg/m³);
short term exposure limit 0.3 ppm (4 mg/m³), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 1.4 mg/m³, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 0.1 ppm (1.4 mg/m³), JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 0.1 ppm (1.4 mg/m³), JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 0.2 mg/m³, Skin, JUN2003
Occupational Exposure Limit - SWITZERLAND MAK- week 0.1 ppm (1.4 mg/m³), DEC2006
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 0.1 ppm;
short term exposure limit 0.3 ppm
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 0.1 ppm;
short term exposure limit 0.3 ppm

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CARBON TETRABROMIDE-air 10 hour time-weighted average 0.1 ppm;
short term exposure limit 0.3 ppm NIOSH* DHHS #95-121,1995
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X4014;
Number of Industries 2;
Total Number of Facilities 34;
Number of Occupations 4;
Total Number of Employees Exposed 2,703;
Total Number of Female Employees Exposed 459

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

REFERENCES:
CODEN
REFERENCE

CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

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SYNONYMS:
Bromid uhlicity (Czech) Carbon bromide Carbon tetrabromide (ACGIH)	Methane, tetrabromide Methane, tetrabromo - Tetrabromomethane

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST	ROUTE/ ORGANISM/ TISSUE	DOSE	REFERENCE
N/R	N/R	N/R	N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
intravenous mouse	lethal dose (50 percent kill): 56 mg/kg	N/R	CSLNX* NX#01612
oral rat	lethal dose : 3 gm/kg	N/R	VCVGH* -,583,1990
subcutaneous mouse	lethal dose (50 percent kill): 298 mg/kg	N/R	TXAPA9 4,354,1962

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ ORGANISM	DOSE	EFFECT	REFERENCE
N/R	N/R	N/R	N/R

REVIEWS:
ORGANIZATION	STANDARD	REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value	time-weighted average 0.1 ppm;short term exposure limit 0.3 ppm	DTLVS* TLV/BEI,2007

STANDARDS AND REGULATIONS:
ORGANIZATION	STANDARD	REFERENCE
Occupational Exposure Limit - AUSTRALIA	time-weighted average 0.1 ppm (1.4 mg/m³), short term exposure limit 0.3 ppm (4.1 mg/m³), JUL2008
Occupational Exposure Limit - BELGIUM	time-weighted average 0.1 ppm(1.4 mg/m³), short term exposure limit 0.3 ppm(4.2 mg/m³), MAR2002
Occupational Exposure Limit - DENMARK	time-weighted average 0.1 ppm (1.4 mg/m³), OCT 2002
Occupational Exposure Limit - FINLAND	time-weighted average 0.1 ppm (1.4 mg/m³), short term exposure limit 0.4 ppm, Skin, JAN1999
Occupational Exposure Limit - FRANCE	VME 0.1 ppm (1.4 mg/m³), FEB2006
Occupational Exposure Limit - KOREA	time-weighted average 0.1 ppm (1.4 mg/m³), short term exposure limit 0.3 ppm (4 mg/m³), 2006
Occupational Exposure Limit - MEXICO	time-weighted average 0.1 ppm (1.4 mg/m³); short term exposure limit 0.3 ppm (4 mg/m³), 2004
Occupational Exposure Limit - THE NETHERLANDS	MAC-TGG 1.4 mg/m³, 2003
Occupational Exposure Limit - NEW ZEALAND	time-weighted average 0.1 ppm (1.4 mg/m³), JAN2002
Occupational Exposure Limit - NORWAY	time-weighted average 0.1 ppm (1.4 mg/m³), JAN1999
Occupational Exposure Limit - RUSSIA	short term exposure limit 0.2 mg/m³, Skin, JUN2003
Occupational Exposure Limit - SWITZERLAND	MAK- week 0.1 ppm (1.4 mg/m³), DEC2006
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN	American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value; time-weighted average 0.1 ppm; short term exposure limit 0.3 ppm
Occupational Exposure Limit IN SINGAPORE, VIETNAM	American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.1 ppm; short term exposure limit 0.3 ppm

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION	STANDARD or SURVEY	REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CARBON TETRABROMIDE-air	10 hour time-weighted average 0.1 ppm; short term exposure limit 0.3 ppm	NIOSH* DHHS #95-121,1995
National Occupational Exposure Survey 1983	National Occupational Exposure Survey 1983: Hazard Code: X4014; Number of Industries 2; Total Number of Facilities 34; Number of Occupations 4; Total Number of Employees Exposed 2,703; Total Number of Female Employees Exposed 459

STATUS IN FEDERAL AGENCIES:
ORGANIZATION	REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

REFERENCES:
CODEN	REFERENCE
CSLNX*	U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
DTLVS*	The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
NIOSH*	National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TXAPA9	Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
VCVGH*	"Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.