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Carbamic acid, methyl - , 2,3 - (dimethylmethylenedioxy) phenyl ester

RTECS #: FC1140000

CAS #: 22781-23-3

UPDATE: February 2009 MW: 223.25 MF: C11H13NO4


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. 1,3 - Benzodioxol - 4 - ol, 2,2 - dimethyl - , methylcarbamate
  2. 1,3 - Benzodioxole, 2,2 - dimethyl - 4 - (N - methylaminocarboxylato) -
  3. 1,3 - Benzodioxole, 2,2 - dimethyl - 4 - (N - methylcarbamato) -
  4. 2,2 - Dimethyl - 1,3 - benzdioxol - 4 - yl N - methylcarbamate
  5. 2,2 - Dimethyl - 1,3 - benzodioxol - 4 - ol methylcarbamate
  6. 2,2 - Dimethyl - 1,3 - benzodioxol - 4 - yl methylcarbamate
  7. 2,2 - Dimethylbenzo - 1,3 - dioxol - 4 - yl methylcarbamate
  8. 2,3 - Isopropylidene - dioxyphenyl methylcarbamate
  9. Bencarbate
  10. Bendiocarb
  11. Bendiocarbe
  12. Carbamic acid, methyl - , 2,3 - (isopropylidenedioxy) phenyl ester
  13. Dycarb
  14. Ficam
  15. Ficam 80W
  16. Ficam D
  1. Ficam ULV
  2. Ficam W
  3. Fisons NC 6897
  4. Garvox
  5. Methylcarbamic acid 2,3 - (isopropylidenedioxy) phenyl ester
  6. Multamat
  7. Multimet
  8. NC6897
  9. Niomil
  10. OMS - 1394
  11. Rotate
  12. Seedox
  13. Seedox 80W
  14. Tatoo
  15. Turcam


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
dog 		lethal dose (50 percent kill): 300 mg/kg N/R HBPTO* 2,1094,2001
oral
guinea pig 		lethal dose (50 percent kill): 35 mg/kg N/R HBPTO* 2,1094,2001
oral
mammal (species unspecified) 		lethal dose (50 percent kill): 35 mg/kg N/R 85KYAH 11,161,1989
oral
mouse 		lethal dose (50 percent kill): 28 mg/kg N/R HBPTO* 2,1094,2001
oral
quail 		lethal dose (50 percent kill): 21 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Ataxia

Lung, Thorax, or Respiration: Dyspnea 		EESADV 8,551,1984
oral
rat 		lethal dose (50 percent kill): 34 mg/kg N/R HBPTO* 2,1094,2001
oral
rabbit 		lethal dose (50 percent kill): 35 mg/kg N/R HBPTO* 2,1094,2001
skin
rat 		lethal dose (50 percent kill): 566 mg/kg N/R HBPTO* 2,1094,2001


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 169 mg/kg/90 day- continuous Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases 		ATSUDG 8,298,1985
oral
rat 		lowest published toxic dose: 562 mg/kg/30 day- continuous Blood: Pigmented or nucleated red blood cells

Blood: Changes in leukocyte (WBC) count

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases 		ATSUDG 8,298,1985


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
REPTED 23,260,2007
TOXICOLOGY REVIEW
JTPAE7 19,1,2006


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Supported RBREV* -,89,1998


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X3209;
Number of Industries 6;
Total Number of Facilities 1,661;
Number of Occupations 6;
Total Number of Employees Exposed 22,364;
Total Number of Female Employees Exposed 907


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA GENETOX PROGRAM 1988, Negative: Aspergillus-aneuploidy


REFERENCES:

CODEN
REFERENCE
85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989
ATSUDG Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978-
EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
HBPTO* Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
JTPAE7 Journal of Toxicologic Pathology. (Nihon Dokusei Byori Gakkai, editor, 3-25-8 Nishi- shinbashi, Minato-ku, Tokyo 105, Japan) V.1- 1988
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987-

Used as an agricultural chemical and pesticide

RTECS Compound Description:
   Agricultural Chemical
   Mutagen

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