RTECS:EN0330000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

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3 - Buten - 2 - one, 4 - phenyl -

RTECS #: EN0330000

CAS #: 122-57-6

UPDATE: October 1997 MW: 146.20 MF: C₁₀H₁₀O

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

SKIN AND EYE IRRITATION DATA:

ACUTE TOXICITY DATA:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

4 - Phenyl - 3 - buten - 2 - one

Benzalaceton (German)

Benzalacetone

Benzylidene acetone

Styryl methyl ketone

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
skin
guinea pig 1%/48 hour moderate JSCCA5 28,357,1977
skin
rabbit 500 mg/24 hour mild FCTXAV 11,1021,1973

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
N/R N/R N/R N/R

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
intraperitoneal
mouse lethal dose (50 percent kill): 1,210 mg/kg N/R ARZNAD 19,617,1969
intravenous
mouse lethal dose (50 percent kill): 112 mg/kg N/R ARZNAD 19,617,1969
oral
rat lethal dose (50 percent kill): 2,031 mg/kg Behavioral: Muscle weakness

Vascular: Regional or general arteriolar or venous dilation

Skin and Appendages: Other: Hair EPASR* 8EHQ-0391-1194

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83179;
Number of Industries 3;
Total Number of Facilities 41;
Number of Occupations 5;
Total Number of Employees Exposed 550
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83179;
Number of Industries 7;
Total Number of Facilities 196;
Number of Occupations 10;
Total Number of Employees Exposed 5,458;
Total Number of Female Employees Exposed 2,178

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

REFERENCES:
CODEN
REFERENCE

ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown.
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7.
JSCCA5 Journal of the Society of Cosmetic Chemists. (Soc. of Cosmetic Chemists, 1995 Broadway, Suite 1701, New York, NY 10023) V.1- 1947-

RTECS Compound Description:
Drug
Primary Irritant

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