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4 - Biphenylol

RTECS #: DV5850000

CAS #: 92-69-3

UPDATE: February 2004 MW: 170.22 MF: C12H10O


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. TUMORIGENIC DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. 4 - Hydroxybiphenyl
  2. 4 - Hydroxydiphenyl
  3. 4 - Phenylphenol
  4. Paraxenol
  1. p - Hydroxybiphenyl
  2. p - Hydroxydiphenyl
  3. p - Phenylphenol


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lowest published toxic dose: 153 gm/kg/78 week- intermittent Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors

Blood: Leukemia 		NTIS** PB223-159
subcutaneous
mouse 		lowest published toxic dose: 1,000 mg/kg Tumorigenic: Carcinogenic by RTECS criteria

Blood: Tumors 		NTIS** PB223-159


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 150 mg/kg N/R NTIS** AD691-490
intraperitoneal
mouse 		lethal dose (50 percent kill): 150 mg/kg Liver: Other changes VCVGK* -,218,1994


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84022;
Number of Industries 1;
Total Number of Facilities 5;
Number of Occupations 2;
Total Number of Employees Exposed 20
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84022;
Number of Industries 1;
Total Number of Facilities 216;
Number of Occupations 1;
Total Number of Employees Exposed 649


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.

RTECS Compound Description:
   Tumorigen

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